Structure elucidation and NMR spectral assignments of three new lignan glycosides from Akebia trifoliatia
Structure elucidation and NMR spectral assignments of three new lignan glycosides from Akebia trifoliatia
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DOI：
10.1002/mrc.2152
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发表时间：
2008-02-01
影响因子：
2
通讯作者：
Guo, De-an
中科院分区：
文献类型：
--
作者：
Guan, Shu-hong;Xia, Jia-meng;Guo, De-an
从三叶木通茎中分离得到三个新的木脂素苷类化合物（1-3）。它们的结构被阐明为：（7 R，8 R，7 'R，8' R）3，3 '，5，5'四甲氧基-4，4 '二羟基-7，9'：7 '，9-二环氧木聚糖-4-O-β-D-吡喃葡萄糖苷（1），（7S，8 S，8' R）-4，4 '，9-三羟基-3，3'，5，5 '-四甲氧基-7，β 9 ′-环氧木聚糖-7 ′-酮9-O-β-D-吡喃葡萄糖苷（2），（7 R，8 R，8'S）-4，4'，9-三羟基-3，3'，5，5'-四甲氧基-7，通过光谱分析（主要是NMR、MS和CD）测定β 9'-环氧木聚糖-7'-酮9-O-β-D-吡喃葡萄糖苷（3）。使用H-1、C-13、DEPT、COSY、HSQC、HMBC和ROESY NMR实验进行化合物的NMR归属。版权所有（c）2007约翰威利父子有限公司。
Three new lignan glycosides (1-3) were isolated from the stems of Akebia trifoliata. Their structures were elucidated as (7R,8R,7'R,8'R)3,3',5,5'tetramethoxy-4,4'dihydroxy-7,9':7',9-diepoxylignan-4-O-beta-D-glucopyranoside(1), (7S,8S,8'R)-4,4',9-trihydroxy-3,3',5,5'-tetramethoxy-7,9'-epoxylignan-7'-one 9-O-beta-D-glucopyranoside (2),(7R,8R,8'S)-4,4',9-trihydroxy3,3',5,5'-tetramethoxy-7,9'-epoxylignan-7'-one 9-O-beta-D-glucopyranoside (3) by spectral analyses, primarily NMR, MS and CD. The NMR assignments for the compounds were carried out using H-1, C-13, DEPT, COSY, HSQC, HMBC and ROESY NMR experiments. Copyright (c) 2007 John Wiley & Sons, Ltd.