Dynamic frame pairing in real-time freehand elastography.
Dynamic frame pairing in real-time freehand elastography.
复制标题
实时徒手弹性成像中的动态框架配对。
DOI：
10.1109/tuffc.2014.2993
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Thittai,ArunKumar
中科院分区：
文献类型：
--
作者：
Xia,Rongmin;Tao,Guozhi;Thittai,ArunKumar
准静态超声（US）弹性成像现在是一种成熟的技术，其涉及在小的准静态压缩之前和之后从成像平面采集US（RF/包络）信号以形成轴向应变弹性图（ASE）。ASE的图像质量是所施加的轴向应变的函数。这种关系被广泛研究，并在文献中的应变滤波器的形式化。弹性成像中的大多数工作通过选择由期望的压缩应变分开的压缩前和压缩后框架来形成弹性图。尽管这种方法在涉及受控压缩的模拟和体外/体内实验中是可行的，但是在真实的时间中徒手压缩期间做到这一点一直是一个挑战。在这项工作中，我们描述了一个预测一个校正方法，动态地选择前和后压缩帧，以形成弹性图，根据所施加的轴向应变水平。我们验证了该方法使用控制压缩实验上的幻影和对比度噪声比（CNRe）方面的动态帧配对方法对连续帧配对方法的性能进行比较。此外，我们证明了新方法的优势与徒手采集数据的帮助下，从幻影实验和在体乳腺数据。结果表明，通过动态方法识别的框架配对与设计用于产生约1%的施加轴向应变的框架配对相匹配。通过传统方法获得的CNRe从低至~5到高达~25变化，这取决于跳跃数和压缩率的选择。然而，动态帧配对方法提供的弹性图的CNRe始终约为20，与压缩率无关。对22个体内乳房数据的分析结果表明，动态配对方法生成的弹性图使得电影回放中每个帧的帧平均轴向应变（FAAS）始终约为1%（0.011 ± 0.001）。
Quasi-static ultrasound (US) elastography is now a well-established technique that involves acquiring US (RF/envelope) signals from an imaging plane before and after a small quasi-static compression to form axial strain elastograms (ASE). The image quality of the ASEs is a function of the applied axial strain. This relationship was extensively investigated and formalized in terms of strain filter in the literature. Most of the work in elastography formed elastograms by choosing pre- and post-compression frames separated by a desired compression strain. Although this approach is feasible in simulations and in vitro/in vivo experiments that involve controlled compression, it has been a challenge to do this during freehand compression in real time. In this work, we describe a one-prediction-one- correction method that dynamically selects pre- and post- compression frames to form an elastogram, based on the applied axial strain level. We validate the method using controlled compression experiments on phantoms and compare the performance of the dynamic frame pairing method against successive-frame pairing method in terms of the contrast-to-noise ratio (CNRe). Further, we demonstrate the advantages of the new method with the help of freehand acquired data from phantom experiments and in vivo breast data. The results demonstrate that the frame-pairing identified by the dynamic method matched the frame pairing that was designed to yield an applied axial strain of ~1%. The CNReobtained by the traditional approach varied from as low as ~5 to as high as ~25, depending on the choice of skip number and compression rate. However, the dynamic frame pairing method provided elastograms with a CNRethat was consistently around ~20, irrespective of the compression rate. The results from analysis of 22 in vivo breast data demonstrated that the dynamic pairing method generated elastograms such that the frame-average axial strain (FAAS) of each frame in the cineloop is consistently ~1% (0.011 ± 0.001).
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