Materials that harness and modulate the immune system.
Materials that harness and modulate the immune system.
复制标题
利用和调节免疫系统的材料。
DOI:
10.1557/mrs.2013.310
复制
发表时间:
2014-01-01
期刊:
影响因子:
5
通讯作者:
Keselowsky BG
中科院分区:
文献类型:
--
作者:
Lewis JS;Roy K;Keselowsky BG
Recently, biomaterial scientists have married materials engineering and immunobiology to conceptualize new immunomodulatory materials. This special class of biomaterials can modulate and harness the innate properties of immune functionality for enhanced therapeutic efficacy. Generally, two fundamental strategies are followed in the design of immunomodulatory biomaterials: (1) immuno-evasive (immuno-mimetic, immuno-suppressing, or immuno-inert) biomaterials and (2) immuno-activating or immuno-enhancing biomaterials. This article highlights the development and application of a number of immunomodulatory materials, categorized by these two general approaches.