Response to emotional stimuli in boys with conduct disorder
Response to emotional stimuli in boys with conduct disorder
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DOI：
10.1176/appi.ajp.162.6.1100
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发表时间：
2005-06-01
影响因子：
17.7
通讯作者：
Herpertz-Dahlmann, B
中科院分区：
文献类型：
--
作者：
Herpertz, SC;Mueller, B;Herpertz-Dahlmann, B
目的：患有品行障碍的男孩在成年后有持续表现出反社会行为的风险，特别是如果他们有注意力缺陷多动障碍（ADHD）的额外诊断。在寻找使儿童易患反社会人格障碍的生物学风险因素时，研究提供了大量数据，表明自主神经低反应性表明未来反社会行为的可能性更大。本研究的目的是探讨自主觉醒的男孩与行为障碍，共病的行为障碍和ADHD，和ADHD only.Method：除了自我评级，皮肤电反应愉快，中性，和不愉快的幻灯片获得了21个男孩与行为障碍和54个男孩与ADHD加行为disorder。43名诊断为ADHD的男孩被招募为临床对照组，43名没有行为障碍或ADHD的男孩被纳入为健康对照组。所有受试者的年龄为8-13岁。结果：与健康受试者和ADHD受试者相比，行为障碍和ADHD+行为障碍的男孩对厌恶刺激的情绪反应水平较低，对所有幻灯片的自主反应水平较低，与效价无关。尽管自我报告的数据支持对明确的恐惧线索的反应不足，心理生理学数据表明，在一个实验环境中，患有行为障碍的男孩，无论是否患有ADHD共病，其特征都是自主反应性的普遍缺陷。不可预测的情感质量的复杂视觉刺激。心理生理学的研究结果可能指出，通常产生适应性认知情绪反应的联想信息处理系统存在缺陷。
Objective: Boys with conduct disorder are at risk of persistently showing antisocial behavior in adult life, particularly if they have an additional diagnosis of attention deficit hyperactivity disorder (ADHD). In the search for biological risk factors that predispose children to the development of antisocial personality disorder, research has provided substantial data suggesting that autonomic hyporesponsiveness indicates a greater likelihood of future antisocial behavior. The purpose of this study was to examine autonomic arousal in boys with conduct disorder, comorbid conduct disorder and ADHD, and ADHD only.Method: In addition to self-ratings, electrodermal responses to pleasant, neutral, and unpleasant slides were obtained for 21 boys with conduct disorder and 54 boys with ADHD plus conduct disorder. Forty-three boys with a diagnosis of ADHD only were recruited as a clinical comparison group, and 43 boys with no conduct disorder or ADHD were included as a healthy comparison group. All subjects were ages 8-13 years.Results: Compared to the healthy subjects and the subjects with ADHD only, the boys with conduct disorder and with ADHD plus conduct disorder reported lower levels of emotional response to aversive stimuli and lower autonomic responses to all slides independent of valence.Conclusions: Although the self-report data supported a deficit in reactivity to explicit fear cues, the psychophysiological data indicated that boys with conduct disorder both with and without a comorbid condition of ADHD are characterized by a generalized deficit in autonomic responsivity in an experimental situation in which children were exposed to complex visual stimuli of unpredictable affective quality. Psychophysiological findings may point to a deficit in associative information processing systems that normally produce adaptive cognitive-emotional reactions.