MORTALITY IN RHEUMATOID-ARTHRITIS, PARTICULARLY AS REGARDS DRUG-USE
MORTALITY IN RHEUMATOID-ARTHRITIS, PARTICULARLY AS REGARDS DRUG-USE
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DOI：
10.3109/03009748509165491
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发表时间：
1985-01-01
影响因子：
2.1
通讯作者：
ALLANDER, E
中科院分区：
文献类型：
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作者：
ALLEBECK, P;RODVALL, Y;ALLANDER, E
对斯德哥尔摩类风湿性关节炎(RA)流行病学调查中调查的239例RA患者进行了长达13年的监测，旨在找出类风湿关节炎(RA)患者高死亡率的原因(S)。所有住院病例都是通过斯德哥尔摩县的住院登记簿确定的。一项基于病历信息的研究对157名在随访期间住院的人进行了研究。比较死亡者和存活者在随访开始时的特征，药物使用情况，以及在随访期间RA以外的疾病。男性和高Steinbrocker功能分级是与死亡风险增加最密切相关的因素。无论是普遍使用药物，还是使用任何特定类型的药物，都不会显著增加死亡风险。我们的结论是，尽管药物使用可能是一个促成因素，但类风湿性关节炎本身，特别是其严重形式的类风湿关节炎是类风湿关节炎患者高死亡率的主要原因。
239 persons with rheumatoid arthritis (RA), previously investigated in an epidemiological survey of RA in Stockholm, were monitored for 13 years with the aim of eliciting the cause(s) of the high mortality among persons with RA. All hospitalizations were identified through the in-patient register of Stockholm County. A study based on medical record information was performed on a group of 157 persons who had been hospitalized during the follow-up. Dead and surviving persons were compared with regard to characteristics at the start of the follow-up, drug use, and diseases other than RA during the follow-up. Male sex and high Steinbrocker functional grading were the factors most closely associated with an increased death risk. Neither drug use generally, nor use of any particular type of drug, significantly increased the death risk. We conclude that, although drug use may be a contributory cause, the disease RA in itself.sbd.and particularly its severe forms.sbd.is the main cause of the high mortality among RA sufferers.