Optical coherence tomographic pattern and focal electroretinogram in patients with retinitis pigmentosa
Optical coherence tomographic pattern and focal electroretinogram in patients with retinitis pigmentosa
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DOI：
10.1038/sj.eye.6703077
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发表时间：
2009-02-01
期刊：
影响因子：
3.9
通讯作者：
Yoshimura, N.
中科院分区：
文献类型：
--
作者：
Oishi, A.;Nakamura, H.;Yoshimura, N.
Purpose The foveal function of patients with retinitis pigmentosa (RP) has been estimated by visual acuity (VA) or visual field (VF) tests. In the present study, the potential of optical coherence tomography (OCT) and focal electroretinogram (fERG) for monitoring macular function in RP patients was investigated. Design Cross-sectional observational study.Methods A total of 56 eyes of 56 patients with RP underwent ophthalmic examination including VA, VF, fERG, and OCT. Patients were morphologically divided into three groups by the appearance of photoreceptor inner/outer segment junction (IS/OS) that were depicted with OCT; type 1: no IS/OS visible, type 2: IS/OS was visible but the length was 2 mm was confirmed. Functional results for VA and fERG were compared and analysed based on the three groups.Results The average VA of type 1 patients was significantly lower than that of types 2 or 3 patients (P
