Historical genomes elucidate European settlement and the African diaspora in Delaware
Historical genomes elucidate European settlement and the African diaspora in Delaware
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历史基因组阐明了特拉华州的欧洲定居点和非洲侨民
DOI：
10.1016/j.cub.2023.04.069
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发表时间：
2023
期刊：
影响因子：
9.2
通讯作者：
Schurr, Theodore G.
中科院分区：
文献类型：
--
作者：
Fleskes, Raquel E.;Owsley, Douglas W.;Bruwelheide, Karin S.;Barca, Kathryn G.;Griffith, Daniel R.;Cabana, Graciela S.;Schurr, Theodore G.
17世纪北美的殖民化将成千上万的欧洲人带到了特拉华州地区的土著土地上，该地区包括切萨皮克湾的东部边界，现在是美国的中大西洋地区。1这些最初的殖民移民的人口特征并不统一，欧洲人和欧美人从其他国家和邻近的殖民地移民到特拉华州地区，他们要么是单身，要么是以家庭为单位的自由人，契约仆人，欧洲殖民者还建立了一种种族化的奴隶制度，通过这种制度，他们强行将数千名非洲人运送到切萨皮克地区。关于特拉华州地区非洲裔个体的历史信息有限，到1700年人口估计不到500人。3，4为了阐明这一时期的人口历史，我们分析了位于特拉华州的艾弗里雷斯特考古遗址（约1675-1725年）的11个个体的低覆盖率基因组。先前的骨骼学和线粒体DNA（mtDNA）序列分析显示，一个由8名欧洲母系血统个体组成的南部群体，被埋在距离北方3名非洲母系血统个体15-20英尺的地方。5常染色体结果进一步阐明了与西北欧参考人群或西非和中非西部参考人群的基因组相似性。我们还确定了三代欧洲血统的母系亲属和非洲血统的成年人和儿童之间的父系亲子关系。这些发现扩展了我们对17世纪末和18世纪初北美的起源和家庭关系的理解。
The 17th-century colonization of North America brought thousands of Europeans to Indigenous lands in the Delaware region, which comprises the eastern boundary of the Chesapeake Bay in what is now the Mid-Atlantic region of the United States.1The demographic features of these initial colonial migrations are not uniformly characterized, with Europeans and European-Americans migrating to the Delaware area from other countries and neighboring colonies as single persons or in family units of free persons, indentured servants, or tenant farmers.2European colonizers also instituted a system of racialized slavery through which they forcibly transported thousands of Africans to the Chesapeake region. Historical information about African-descended individuals in the Delaware region is limited, with a population estimate of less than 500 persons by 1700 CE.3,4To shed light on the population histories of this period, we analyzed low-coverage genomes of 11 individuals from the Avery's Rest archaeological site (circa 1675–1725 CE), located in Delaware. Previous osteological and mitochondrial DNA (mtDNA) sequence analyses showed a southern group of eight individuals of European maternal descent, buried 15–20 feet from a northern group of three individuals of African maternal descent.5Autosomal results further illuminate genomic similarities to Northwestern European reference populations or West and West-Central African reference populations, respectively. We also identify three generations of maternal kin of European ancestry and a paternal parent-offspring relationship between an adult and child of African ancestry. These findings expand our understanding of the origins and familial relationships in late 17thand early 18thcentury North America.
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影响因子：
64.8
作者：
Gurdasani, Deepti;Carstensen, Tommy;Tekola-Ayele, Fasil;Pagani, Luca;Tachmazidou, Ioanna;Hatzikotoulas, Konstantinos;Karthikeyan, Savita;Iles, Louise;Pollard, Martin O.;Choudhury, Ananyo;Ritchie, GrahamR. S.;Xue, Yali;Asimit, Jennifer;Nsubuga, Rebecca N.;Young, Elizabeth H.;Pomilla, Cristina;Kivinen, Katja;Rockett, Kirk;Kamali, Anatoli;Doumatey, Ayo P.;Asiki, Gershim;Seeley, Janet;Sisay-Joof, Fatoumatta;Jallow, Muminatou;Tollman, Stephen;Mekonnen, Ephrem;Ekong, Rosemary;Oljira, Tamiru;Bradman, Neil;Bojang, Kalifa;Ramsay, Michele;Adeyemo, Adebowale;Bekele, Endashaw;Motala, Ayesha;Norris, Shane A.;Pirie, Fraser;Kaleebu, Pontiano;Kwiatkowski, Dominic;Tyler-Smith, Chris;Rotimi, Charles;Zeggini, Eleftheria;Sandhu, Manjinder S.
通讯作者：
Sandhu, Manjinder S.
圣赫勒拿岛解放非洲人的遗传起源
DOI：
--
发表时间：
2019
期刊：
bioRxiv
影响因子：
--
作者：
Marcela Sandoval;Anuradha Jagadeesan;Anuradha Jagadeesan;María C. Ávila;Shyam Gopalakrishnan;Jazmín Ramos;J. V. Moreno;J. V. Moreno;J. V. Moreno;Gabriel Renaud;D. I. Cruz;D. I. Cruz;E. Johannesdóttir;J. Watson;K. Robson;A. Pearson;A. Helgason;Agnar Helgason;M. Gilbert;M. Gilbert;H. Schroeder
通讯作者：
H. Schroeder
根据基因型或低深度测序数据对密切家族关系进行无等位基因频率推断
DOI：
--
发表时间：
2019
期刊：
影响因子：
--
作者：
R. Waples
通讯作者：
R. Waples
影响因子：
2.8
作者：
AUFDERHEIDE, AC;ANGEL, JL;WITTMERS, LE
通讯作者：
WITTMERS, LE
影响因子：
2.1
作者：
Carvalho, Bruno Maia;Bortolini, Maria Cátira;Ribeiro-dos-Santos, Ândrea Kely Campos
通讯作者：
Ribeiro-dos-Santos, Ândrea Kely Campos