Two new isomers of domoic acid from a red alga, Chondria armata
Two new isomers of domoic acid from a red alga, Chondria armata
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DOI：
10.1016/s0041-0101(96)00123-7
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发表时间：
1997-02-01
期刊：
影响因子：
2.8
通讯作者：
Noguchi, T
中科院分区：
文献类型：
--
作者：
Zaman, L;Arakawa, O;Noguchi, T
异冬酰胺酸 G 和 H 是神经毒素软骨藻酸的两种新异构体，以及异冬酰胺酸 A、B、E 和 F，是从九州岛南端收集的红藻阿玛塔软骨藻中分离出来的。基于电喷雾电离质量和[H-1]核磁共振谱分析（包括[H-1-H-1]相关光谱和核欧沃豪塞效应相关光谱），其中两种的结构被推断为2-羧基-4-(5-羧基-1-甲基-2-己烯亚基)-3-吡咯烷乙酸的(E,E)和(Z,E)异构体。 (C) 1997 爱思唯尔科学有限公司。
Isodomoic acids G and H, two new isomers of the neurotoxin domoic acid, along with isodomoic acids A, B, E and F, were isolated from a red alga, Chondria in armata, collected at the southern tip of Kyushu Island. The structures of two of these were deduced to be (E, E) and (Z, E) isomers of 2-carboxy-4-(5-carboxy-1-methyl-2-hexenylidene)-3-pyrrolidineacetic acid, based on electrospray ionization mass and [H-1]nuclear magnetic resonance spectral analyses including [H-1-H-1]correlation spectroscopy and nuclear Overhauser effect correlation spectroscopy. (C) 1997 Elsevier Science Ltd.