Urinary Tract Infections in Women

Urinary Tract Infections in Women
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DOI:
10.1016/j.mcna.2010.08.023
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发表时间:
2011-01-01
影响因子:
5.9
通讯作者:
Schaeffer, Anthony J.
Schaeffer, Anthony J.
中科院分区:
医学2区
文献类型:
--
作者:
Dielubanza, Elodi J.;Schaeffer, Anthony J.

文献摘要

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尿路感染(UTI)是全世界女性中最常见的肠外传染病,由于其高患病率、频繁复发以及在快速发展的抗菌药物耐药性的背景下可能出现的无数相关发病率,这可能是临床实践中最艰巨的挑战之一。及时缓解症状、控制感染以及预防发病、耐药微生物生长和复发感染往往很困难。本文综述了女性尿路感染的流行病学和发病机制;描述常见感染模式、临床危险信号以及适当的实验室检测和成像;探索新出现的抗菌药物耐药性模式;并审查了女性单纯性尿路感染治疗的最新指南。
Urinary tract infection (UTI) is the most common extraintestinal infectious disease entity in women worldwide, and perhaps one of the most formidable challenges in clinical practice given its high prevalence, frequent recurrence, and myriad associated morbidities in the setting of rapidly evolving antimicrobial resistance. Achieving timely symptom relief and infection control and preventing morbidity, growth of resistant organisms, and recurrent infection are often difficult. This article reviews epidemiology and pathogenesis of urinary tract infection in women; characterizes common patterns of infection, clinical red flags, and appropriate laboratory testing and imaging; explores emerging patterns of antimicrobial resistance; and reviews the updated guidelines for the treatment of uncomplicated UTI in women.