Prevalence of vitamin D depletion among morbidly obese patients seeking gastric bypass surgery.
Prevalence of vitamin D depletion among morbidly obese patients seeking gastric bypass surgery.
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DOI：
10.1016/j.soard.2005.12.001
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发表时间：
2006-03-01
期刊：
影响因子：
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通讯作者：
Talpos, Gary B
中科院分区：
文献类型：
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作者：
Carlin, Arthur M;Rao, D Sudhaker;Talpos, Gary B
背景：据报道，减肥手术后钙和维生素D代谢下降。本研究的目的是评估胃旁路手术前病态肥胖患者的维生素D营养状况。方法：我们前瞻性研究了279例病态肥胖患者寻求胃旁路手术维生素D营养状况评估血清25-羟维生素D水平。此外，分析血清样本的钙，碱性磷酸酶（AP），全段甲状旁腺激素（PTH），和1，25-二羟维生素D。结果：平均患者年龄为43 +/- 9岁，87%的研究患者是女性，72%是白色。88%和89%的患者血清钙和AP水平正常。维生素D缺乏，定义为血清25-羟基维生素D水平
BACKGROUND: Abnormalities in calcium and vitamin D metabolism have been reported after bariatric surgery. The purpose of this study was to evaluate vitamin D nutritional status among morbidly obese patients before gastric bypass surgery.METHODS: We prospectively studied 279 morbidly obese patients seeking gastric bypass surgery for vitamin D nutritional status as assessed by serum 25-hydroxyvitamin D level. In addition, serum samples were analyzed for calcium, alkaline phosphatase (AP), intact parathyroid hormone (PTH), and 1,25-dihydroxyvitamin D.RESULTS: Mean patient age was 43 +/- 9 years; 87% of the study patients were women, and 72% were white. Serum calcium and AP levels were normal in 88% and 89% of the patients, respectively. Vitamin D depletion, defined as serum 25-hydroxyvitamin D level