Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentation.
Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentation.
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DOI：
10.1097/anc.0b013e31821baaf4
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发表时间：
2011-06
期刊：
影响因子：
--
通讯作者：
Van Marter LJ
中科院分区：
文献类型：
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作者：
Gregory KE;Deforge CE;Natale KM;Phillips M;Van Marter LJ
坏死性小肠结肠炎（NEC）仍然是与早产相关的最灾难性的合并症之一。尽管进行了广泛的研究，但该疾病仍未得到解决。本文的目的是介绍 NEC 发病机制的科学现状，总结该疾病的临床表现和严重程度分期，并强调早期识别 NEC 和对诊断患有这种胃肠道疾病的婴儿进行持续护理所需的护理评估。介绍了对护理评估最敏感并与贝尔分期标准相关的全身和肠道临床体征的分布。该描述性数据代表了 117 例低胎龄婴儿（妊娠 <29 周）诊断的 NEC 病例。这些数据突出了 NEC 婴儿中最常见的临床症状，从而为 NEC 婴儿的评估和护理提供了循证指南。
Necrotizing enterocolitis (NEC) remains one of the most catastrophic comorbidities associated with prematurity. In spite of extensive research, the disease remains unsolved. The aims of this paper are to present the current state of the science on the pathogenesis of NEC, summarize the clinical presentation and severity staging of the disease, and highlight the nursing assessments required for early identification of NEC and ongoing care for infants diagnosed with this gastrointestinal disease. The distributions of systemic and intestinal clinical signs that are most sensitive to nursing assessment and associated with Bell Staging Criteria are presented. This descriptive data is representative of 117 cases of NEC diagnosed in low gestational age infants (<29 weeks gestation). The data highlights the clinical signs most commonly observed in infants with NEC, and thus, provides NICU nurses an evidence-based guide for assessment and care of infants with NEC.