Design of magnetic polyplexes taken up efficiently by dendritic cell for enhanced DNA vaccine delivery
Design of magnetic polyplexes taken up efficiently by dendritic cell for enhanced DNA vaccine delivery
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DOI：
10.1038/gt.2013.77
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发表时间：
2014-02-01
期刊：
影响因子：
5.1
通讯作者：
Plebanski, M.
中科院分区：
文献类型：
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作者：
AL-Deen, F. M. Nawwab;Selomulya, C.;Plebanski, M.
树突状细胞 (DC) 靶向疫苗需要高效率的摄取，然后是 DC 的激活和成熟。我们使用的磁性载体包含聚乙烯亚胺（PEI）涂层的超顺磁性氧化铁纳米颗粒，以及不同分子量的透明质酸（HA）（
Dendritic cells (DC) targeting vaccines require high efficiency for uptake, followed by DC activation and maturation. We used magnetic vectors comprising polyethylenimine (PEI)-coated superparamagnetic iron oxide nanoparticles, with hyaluronic acid (HA) of different molecular weights (