Chronic abruption-oligohydramnios sequence.
Chronic abruption-oligohydramnios sequence.
复制标题
慢性早剥-羊水过少序列。
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
H. Finberg
中科院分区：
文献类型：
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作者：
J. Elliott;B. Gilpin;Strong Th;H. Finberg
目的
确定慢性便秘患者的结局。
研究设计
对54个月期间在三级医疗中心分娩的所有患者进行了回顾性分析。所有诊断为胎盘脱垂伴羊水过少或胎膜破裂的患者均纳入研究。慢性胎盘早剥-羊水过少序列（CAOS）由以下标准定义：（1）在没有前置胎盘或其他可识别出血来源的情况下出现临床显着的阴道出血，（2）最初记录的羊水量正常，以及（3）羊水过少（羊水指数<或= 5）最终发展，但没有同时出现破膜的证据。
结果
24例CAOS患者被确定。14例在胎龄< 20周时首次出现流产迹象。在18/24例中，在绒毛膜和子宫之间发现了凝块。首次出血事件的平均胎龄为19.4 ± 5.5（SD）周，分娩时的平均胎龄为28.1 ± 4.5周。15/24例发生早产胎膜早破。在这15例患者中，诊断羊水过少和诊断胎膜破裂之间的平均时间为11.5 +/-天。第一次出血发生在妊娠< 20周的患者的胎龄为26.1 +/- 3.9周，对照组为33.0 +/- 5.3周。
结论
CAOS可发生在妊娠合并胎盘早剥。如果发生，分娩时的平均胎龄为28周。
OBJECTIVE
To determine outcome in patients with chronic abruption.
STUDY DESIGN
A retrospective review was performed of all patients delivering at a tertiary medical center during a 54-month period. All patients with a diagnosis of placental abruption with oligohydramnios or ruptured membranes were included. Chronic abruption-oligohydramnios sequence (CAOS) was defined by the following criteria: (1) clinically significant vaginal bleeding in the absence of placenta previa or other identifiable source of bleeding, (2) amniotic fluid volume initially documented as normal, and (3) oligohydramnios (amniotic fluid index < or = 5) eventually developing without concurrent evidence of ruptured membranes.
RESULTS
Twenty-four patients with CAOS were identified. Fourteen had first evidence of abruption at < 20 weeks' gestational age. A clot was identified between the chorion and uterus in 18/24. The mean gestational age at the first bleeding episode was 19.4 +/- 5.5 (SD) weeks, with the mean gestational age at delivery 28.1 +/- 4.5 weeks. Preterm premature membrane rupture occurred in 15/24. In these 15 there was a mean of 11.5 +/- days between the diagnosis of oligohydramnios and of ruptured membranes. Patients whose first blood occurred at < 20 weeks' gestation delivered at a gestational age of 26.1 +/- 3.9 weeks versus 33.0 +/- 5.3 weeks for the control group.
CONCLUSION
CAOS can occur in pregnancies complicated by abruptio placentae. If it develops, the mean gestational age at delivery is 28 weeks.