Mechanical loading of rigid intramuscular implants.
Mechanical loading of rigid intramuscular implants.
复制标题
刚性肌内植入物的机械负载。
DOI：
10.1007/s10544-006-9031-5
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发表时间：
2007
影响因子：
2.8
通讯作者：
Bryant,JTimothy
中科院分区：
文献类型：
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作者：
Loeb,GeraldE;Peck,RaymondA;Singh,Jasspreet;Kim,Young-Ho;Deshpande,Sudeep;Baker,LucindaL;Bryant,JTimothy
几个小组正在开发一种新类型的无铅永久植入电子设备的不同版本，其尺寸和形状因素允许它们被注入肌肉(BIONS™)。它们的电路由薄壁密封胶囊保护，使其免受体液的影响，这些胶囊由坚硬和易碎的材料(玻璃或陶瓷)制成，其中包括对电极的馈通。这些包裹经历了由它们所刺激的收缩所产生的反复压力。我们在此提供此类压力的最坏情况分析，以及用于测试和验证用于此类用途的设备的方法，以及针对经历意外故障的设计的故障分析和补救策略。
Several groups are developing different versions of a new class of leadless, permanently implanted electronic devices with a size and form factor that allows them to be injected into muscles (BIONs™). Their circuitry is protected from body fluids by thin-walled hermetic capsules made from rigid and brittle materials (glass or ceramic) that include feedthroughs to their electrodes. These packages experience repetitive stresses from the very contractions that they excite. We here provide a worst-case analysis of such stresses and methods for testing and validation of devices intended for such usage, along with the failure analysis and remediation strategy for a design that experienced unanticipated failuresin vivo.