Epidemiology of functional dyspepsia: A global perspective

Epidemiology of functional dyspepsia: A global perspective
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DOI:
10.3748/wjg.v12.i17.2661
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发表时间:
2006-05-07
影响因子:
4.3
通讯作者:
Goh, Khean-Lee
Goh, Khean-Lee
中科院分区:
医学2区
文献类型:
--
作者:
Mahadeva, Sanjiv;Goh, Khean-Lee

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消化不良是指成人常见的一组上消化道症状。众所周知,消化不良是由器质性原因引起的,但大多数患者患有非溃疡或功能性消化不良。对不同地理位置基于人群的研究的流行病学数据进行了审查,因为它们提供了更现实的信息。由于排除大量人群的结构性疾病存在逻辑困难,因此基于人群的真正功能性消化不良(FD)研究很少。在全球范围内,未经调查的消化不良 (UD) 的患病率在 7%-45% 之间变化,具体取决于所使用的定义和地理位置,而 FD 的患病率在 11%-29.2% 之间变化。 FD 的危险因素已被证明包括女性和潜在的心理障碍,而环境/生活方式习惯,如社会经济地位不佳、吸烟、咖啡因摄入量增加和非甾体抗炎药的摄入似乎与 UD 更相关。显然,消化不良,尤其是 FD 是全球常见疾病,影响着大多数人群,无论身在何处。 (C) 2006 年 WJG 出版社。版权所有。
Dyspepsia refers to group of upper gastrointestinal symptoms that occur commonly in adults. Dyspepsia is known to result from organic causes, but the majority of patients suffer from non-ulcer or functional dyspepsia. Epidemiological data from population-based studies of various geographical locations have been reviewed, as they provide more realistic information. Population-based studies on true functional dyspepsia (FD) are few, due to the logistic difficulties of excluding structural disease in large numbers of people. Globally, the prevalence of uninvestigated dyspepsia (UD) varies between 7%-45%, depending on definition used and geographical location, whilst the prevalence of FD has been noted to vary between 11%-29.2%. Risk factors for FD have been shown to include females and underlying psychological disturbances, whilst environmental/lifestyle habits such as poor socio-economic status, smoking, increased caffeine intake and ingestion of non-steroidal anti-inflammatory drugs appear to be more relevant to UD. It is clear that dyspepsia and FD in particular are common conditions globally, affecting most populations, regardless of location. (C) 2006 The WJG Press. All rights reserved.