Driving the Scalability of DNA-Based Information Storage Systems
Driving the Scalability of DNA-Based Information Storage Systems
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DOI：
10.1021/acssynbio.9b00100
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发表时间：
2019-06-01
影响因子：
4.7
通讯作者：
Keung, Albert J.
中科院分区：
文献类型：
--
作者：
Tomek, Kyle J.;Volkel, Kevin;Keung, Albert J.
DNA的密度极高，与目前的存储介质相比具有令人信服的优势;然而，为了达到实际能力，需要新的组织和访问信息的系统。在这里，我们使用化学句柄从模拟5 TB数据的复杂DNA数据库中选择性地提取独特的文件，并设计和实现一个嵌套的文件地址系统，将DNA存储系统的理论最大容量提高了五个数量级。这些进步使得具有调制解调器容量和文件访问能力的基于DNA的数据存储系统的开发和未来扩展成为可能。
The extreme density of DNA presents a compelling advantage over current storage media; however, to reach practical capacities, new systems for organizing and accessing information are needed. Here, we use chemical handles to selectively extract unique files from a complex database of DNA mimicking 5 TB of data and design and implement a nested file address system that increases the theoretical maximum capacity of DNA storage systems by five orders of magnitude. These advancements enable the development and future scaling of DNA-based data storage systems with modem capacities and file access capabilities.