A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease

A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease
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DOI:
10.1053/gast.2002.35988
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发表时间:
2002-10-01
期刊:
影响因子:
29.4
通讯作者:
Marano, P
Marano, P
中科院分区:
医学1区
文献类型:
--
作者:
Costamagna, G;Shah, SK;Marano, P

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背景和目标:本研究旨在前瞻性比较小肠X线片与无线胶囊式内窥镜的临床结局。方法:连续选择22例疑似小肠疾病的患者。2例患者因回肠狭窄被排除。因此,钡剂后续和Given M2 A无线视频胶囊(Given Imaging Ltd.,Yoqneam,以色列)内镜检查进行了比较,在20例患者(13名男性,平均年龄,52.5岁,范围,29-78岁)。结果:17例钡剂造影正常,3例回肠结节。3例患者的胶囊式内窥镜检查正常,其余17例患者显示阳性结果。4例(20%)患者的钡剂检查被认为是诊断性的。9例(45%)患者的胶囊式内窥镜检查被认为是诊断性的,8例(40%)患者的胶囊式内窥镜检查被认为是可疑的,3例(15%)患者的胶囊式内窥镜检查失败。对于不明原因消化道出血,钡剂随访的诊断潜力远低于胶囊内镜(5% vs.31%,P < 0.05)。与最近进行的内窥镜检查相比,胶囊式内窥镜检查耐受性良好,患者接受度更高。结论:电子胶囊内镜对小肠疾病的诊断价值优于小肠X线平片,具有上级价值。然而,这种新型的无线内窥镜系统需要进一步评估,因为其局限性,如难以解释潜在的非特异性发现。
Background & Aims: This study was undertaken to prospectively compare the clinical outcomes of small bowel radiographs with the wireless capsule endoscopy. Methods: Twenty-two patients were selected consecutively because of suspected small bowel disease. Two patients were excluded owing to ileal stenosis. Thus, the results of barium follow-through and the Given M2A wireless video capsule (Given Imaging Ltd., Yoqneam, Israel) endoscopy were compared in 20 patients (13 men; mean age, 52.5 yr; range, 29-78 yr). Results: Barium follow-through was normal in 17 patients and showed ileal nodularity in 3 patients. Capsule endoscopy was normal in 3 patients and showed positive findings in the remaining :17 patients. The barium study was considered diagnostic in 4 (20%) patients. The capsule endoscopy was considered diagnostic in 9 (45%) patients, suspicious in 8 (40%) patients, and failed in 3 (15%) patients. For obscure gastrointestinal (GI) bleeding, the diagnostic potential of barium follow-through was much worse as compared with the capsule endoscopy (5% vs. 31%, P < 0.05). Capsule endoscopy was well tolerated and better accepted by patients when compared with the most recently performed endoscopic procedure. Conclusions: The video capsule endoscope was found to be superior to small bowel radiograph for evaluation of small bowel diseases. However, this novel wireless endoscope system needs further assessment because of limitations such as difficulties in interpretation of potentially nonspecific findings.