Preliminary Measurements with MicroSQUID
Preliminary Measurements with MicroSQUID
复制标题
使用 MicroSQUID 进行初步测量
DOI：
10.1007/978-1-4613-0581-1_152
复制
发表时间：
1989
影响因子：
9
通讯作者：
D. S. Buchanan
中科院分区：
文献类型：
--
作者：
J. Wikswo;R. Friedman;A. Kilroy;J. M. V. Egeraat;D. S. Buchanan
众所周知，为了获得最佳灵敏度，SQUID生物磁强计的拾取线圈的直径应不小于源与线圈的间距，而这一距离是磁强计空间分辨率的主要决定因素（Roth等人，1989）。因此，采用传统杜瓦的SQUID系统通常具有10至20毫米的空间分辨率，如果以成像电流分布的能力（Roth等人，1989）或解析两个紧密间隔的偶极电流源的能力来测量分辨率（Tan等人，1989）。虽然1至2厘米的分辨率对许多人体研究来说是足够的，但对体外制剂（如分离的神经和肌肉以及大脑和心脏组织切片）的实验将受益于1至2毫米的分辨率。由于这些源的磁场在l/r2到l/ r3时衰减，因此用绝对磁强计灵敏度来减小线圈到源的间距是有利的（Roth et al. 1989; Wikswo, 1988）。我们描述了用4通道SQUID梯度仪进行的测量，其直径为3mm的拾取线圈位于距离杜瓦瓶外表面1.4 mm处（Buchanan等人，1989）。
It is well known that for optimum sensitivity, the diameter of the pickup coil for a SQUID biomagnetometer should be no less than the source-to-coil spacing, and that this distance is the primary determinant of the spatial resolution of the magnetometer (Roth et al., 1989). As a result, SQUID systems with conventional Dewars typically have spatial resolutions of 10 to 20 mm when resolution is measured in terms of the ability either to image a current distribution (Roth et al., 1989) or to resolve two closely-spaced dipolar current sources (Tan et al., 1989). While 1 to 2 cm resolution is adequate for many studies on humans, experiments on in vitro preparations such as isolated nerves and muscles and slices of brain and cardiac tissue would benefit from 1 to 2 mm resolution. Because the fields from these sources fall off as l/r2 to l/ r3, it can be advantageous to trade absolute magnetometer sensitivity for decreased coil-to-source spacing (Roth et al. 1989; Wikswo, 1988). We describe measurements made with a 4-channel SQUID gradiometer whose 3 mm diameter pickup coils are located 1.4 mm from the outer surface of the Dewar (Buchanan, et al., 1989).
皮质电流源的磁场：空间滤波模型在正向和逆向问题中的应用。
DOI：
10.1016/0013-4694(90)90059-s
发表时间：
1990
期刊：
Electroencephalography and clinical neurophysiology
影响因子：
--
作者：
Tan,S;Roth,BJ;WikswoJr,JP
通讯作者：
WikswoJr,JP