Discordance Between Fractional Flow Reserve and Coronary Flow Reserve Insights From Intracoronary Imaging and Physiological Assessment

Discordance Between Fractional Flow Reserve and Coronary Flow Reserve Insights From Intracoronary Imaging and Physiological Assessment
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DOI:
10.1016/j.jcin.2017.03.006
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发表时间:
2017-05-22
影响因子:
11.3
通讯作者:
Samady, Habib
Samady, Habib
中科院分区:
医学1区
文献类型:
--
作者:
Ahn, Sung Gyun;Suh, Jon;Samady, Habib

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目的探讨冠脉血流储备分数(FFR)和冠脉血流储备(CFR)值不一致的心外膜和微血管底物。背景:FFR、充血性狭窄阻力(HSR)和血管内超声作为评价心外膜功能的指标,CFR和充血微血管阻力(HMR)作为微血管功能的指标,对94例中度冠脉狭窄患者进行检测。根据FFR的值计算4个象限的最大斑块负荷(PBmax)、HSR和HMR
OBJECTIVES The aim of this study was to investigate the epicardial and microvascular substrates associated with discordances between fractional flow reserve (FFR) and coronary flow reserve (CFR) values.BACKGROUND Discordances between FFR and CFR remain poorly characterized.METHODS FFR, hyperemic stenosis resistance (HSR), and intravascular ultrasound were performed as indexes of epicardial function and CFR and hyperemic microvascular resistance (HMR) as measures of microvascular function in 94 patients with moderate coronary stenosis. Maximal plaque burden (PBmax), HSR, and HMR were calculated in 4 quadrants based on values of FFR