The Japanese version of the Rapid Dementia Screening Test is effective compared to the clock-drawing test for detecting patients with mild Alzheimer's disease
The Japanese version of the Rapid Dementia Screening Test is effective compared to the clock-drawing test for detecting patients with mild Alzheimer's disease
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DOI：
10.1111/psyg.12144
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发表时间：
2016-07-01
期刊：
影响因子：
2
通讯作者：
Mimura, Masaru
中科院分区：
文献类型：
--
作者：
Moriyama, Yasushi;Yoshino, Aihide;Mimura, Masaru
背景日本版的痴呆症快速筛查测试（RDST-J）和画钟测试（CDT）都是用于检测阿尔茨海默病严重程度的简短心理测量筛查工具。然而，目前尚不清楚哪种方法在筛查轻度阿尔茨海默病时更有效。方法我们对 250 名患有极轻度至重度阿尔茨海默病的患者和 49 名健康志愿者进行了 RDST-J 和 CDT。简易精神状态检查得分为12-26的患者的临床痴呆评分(CDR)评分为0.5至3。根据CDR评分将患者分为四组。我们根据 CDT 和 RDST-J 评分在四组和对照受试者之间进行单因素方差分析。结果数据分析显示，RDST-J 可以区分 CDR 0.5 的患者与对照，但 CDT 不能。此外，RDST-J 评分 8 分的敏感性为 57.1%，特异性为 81.0%，RDST-J 评分 9 分的敏感性为 79.6%，特异性为 55.1%，区分 CDR 0.5 与对照。结论 RDST-J 是区分 CDR 0.5 与对照的比 CDT 更有效的工具。
BackgroundThe Japanese version of the Rapid Dementia Screening Test (RDST-J) and the clock-drawing test (CDT) are both brief psychometric screening tools used to detect the severity of Alzheimer's disease. It remains unclear, however, which is more effective when screening for mild Alzheimer's disease.MethodsWe administered the RDST-J and CDT to 250 patients with very mild to severe Alzheimer's disease and to 49 healthy volunteers. Patients with a Mini-Mental State Examination score of 12-26 had Clinical Dementia Rating (CDR) scores from 0.5 to 3. Patients were divided into four groups according to CDR score. We performed one-way factorial anova between the four groups and control subjects based on the CDT and RDST-J scores.ResultsData analysis revealed that RDST-J could distinguish patients with CDR 0.5 from the controls, but CDT could not. Furthermore, the sensitivity of a RDST-J score 8 was 57.1%, with a specificity of 81.0%, and the sensitivity of a RDST-J score 9 was 79.6%, with a specificity of 55.1% for discriminating CDR 0.5 from controls.ConclusionsRDST-J is a more effective tool than CDT for distinguishing CDR 0.5 from controls.