The association of psychosocial stress and bacterial vaginosis in a longitudinal cohort
The association of psychosocial stress and bacterial vaginosis in a longitudinal cohort
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DOI：
10.1016/j.ajog.2005.07.047
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发表时间：
2006-02-01
影响因子：
9.8
通讯作者：
Klebanoff, MA
中科院分区：
文献类型：
--
作者：
Nansel, TR;Riggs, MA;Klebanoff, MA
目的：本研究的目的是评估心理社会压力与细菌性阴道病在一个纵向样本的非孕妇women.Study设计：一个为期1年的前瞻性纵向设计。在常规卫生保健访视时招募了年龄为15至44岁的非妊娠女性（n = 3614）。每季度进行一次评估，为期一年，包括标准化盆腔检查，临床症状评估和广泛的自我报告访谈。（校正比值比，1.10; 95% CI，1.01 - 1.20）和细菌性阴道病的发病率增加（校正比值比，1.29; 95% CI，1.12 - 1.48）。压力和细菌性阴道病发病率之间的关联没有明显改变的控制行为和人口统计学特征，并放大（优势比，2.05; 95%CI，1.15 - 3.66）在一个病例交叉analysis.Conclusion：增加心理社会压力与更大的细菌性阴道病的患病率和发病率独立于其他危险因素。(c)2006 Mosby，Inc. All rights reserved.
Objective: The purpose of this study was to assess the association of psychosocial stress with bacterial vaginosis in a longitudinal sample of nonpregnant women.Study design: A 1-year prospective longitudinal design was used. Nonpregnant women (n = 3614) aged 15 to 44 years were recruited at routine health care visits. Assessments were conducted quarterly for I year and included a standardized pelvic examination, an assessment of clinical symptoms, and an extensive self-report interview.Results: Psychosocial stress was associated with overall prevalence of (adjusted odds ratio, 1.10; 95% Cl, 1.01-1.20) and an increased incidence of (adjusted odds ratio, 1.29; 95% CI, 1.12-1.48) bacterial vaginosis. The association between stress and bacterial vaginosis incidence was not changed appreciably by the control for behavioral and demographic characteristics and was magnified (odds ratio, 2.05; 95% CI, 1.15-3.66) in a case-crossover analysis.Conclusion: Increased psychosocial stress is associated with greater bacterial vaginosis prevalence and incidence independent of other risk factors. (c) 2006 Mosby, Inc. All rights reserved.