Collagenous fibril texture of the human knee joint menisci
Collagenous fibril texture of the human knee joint menisci
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DOI：
10.1007/s004290050141
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发表时间：
1998-04-01
期刊：
影响因子：
--
通讯作者：
Tillmann, B
中科院分区：
文献类型：
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作者：
Petersen, W;Tillmann, B
解剖学和临床文献描述了人类半月板中胶原原纤维的排列为“拱廊状”。偏振光显微研究发现，内周长以径向为主，外周长以圆形为主，呈“拱廊状”取向。然而，这并不能提供半月板撕裂方向的力学解释。鉴于这一矛盾，我们逐层暴露18 ~ 85岁成人半月板中的胶原原纤维，用扫描电镜研究其排列。所得结果与分裂线的路径进行了比较。扫描电镜显示半月板横截面上有三个不同的层：(1)半月板表面的胫骨和股侧被直径约30 nm的薄原纤维网覆盖。(2)在浅网下，胫骨和股表面有一层片状胶原原纤维束。在前、后节的外周区域，胶原原纤维束呈放射状排列。在所有其他部位，胶原纤维束以不同角度相交。(3)半月板胶原原纤维的主要部分位于股骨和胫骨表层之间的中心区域。在半月板中央主要部分的各处，胶原纤维束呈圆形排列。半月板内周长区域的分割线以圆形方式布置，一般在靠近底座的部分沿径向运行。扫描电镜显示，分裂线的方向取决于胶原原纤维在浅板层的方向。文献中描述的胶原原纤维的拱廊状路径既不能通过扫描电子显微镜也不能通过分裂线的过程来证实。半月板中心部分胶原原纤维的圆形排列为半月板组织中大部分撕裂的纵向方向提供了功能解释。
Anatomical and clinical literature describes the arrangement of collagen fibrils in the human meniscus as being "arcade-like". The "arcade-like" orientation, mainly running in a radial direction in the internal circumference and in a circular direction in the external circumference, was found in polarization light microscopic studies. This, however, does not provide a mechanical explanation for the direction of meniscus tears. In view of this contradiction collagen fibrils in the menisci of adults aged from 18 to 85 years were exposed layer-by-layer to study their arrangement by scanning electron microscopy. The results obtained by this procedure were compared to the path of the split lines. Scanning electron microscopy reveals three distinct layers in the meniscus cross section: (1) The tibial and femoral sides of the meniscus surfaces are covered by a meshwork of thin fibrils with a diameter of approximately 30 nm. (2) Beneath the superficial network there is a layer of lamellalike collagen fibril bundles on the tibial and femoral surface. In the area of the external circumference of the anterior and posterior segments the bundles of collagen fibrils are arranged in a radial direction. In all other parts the collagen fibril bundles intersect at various angles. (3) The main portion of the meniscus collagen fibrils are located in the central region between the femoral and the tibial surface layers. Everywhere in the central main portion of the meniscus the bundles of collagen fibrils are orientated in a circular manner. The split lines in the region of the internal circumference of the menisci are arranged in a circular manner, generally running in a radial direction in the portions adjacent to the base. Scanning electron microscopy reveals that the direction of the split lines depends on the orientation of the collagen fibrils in the superficial lamellar layer. The arcade-like path of the collagen fibrils described in the literature can not be confirmed either by scanning electron microscopy or by the course of the split lines. The circular arrangement of collagen fibrils in the central portion of the meniscus provides a functional explanation for the longitudinal orientation of the majority of tears in the meniscus tissue.