Neutrophil-erythrocyte rosettes suggestive of Coombs-negative autoimmune haemolysis.
Neutrophil-erythrocyte rosettes suggestive of Coombs-negative autoimmune haemolysis.
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DOI：
10.1016/s2352-3026(21)00373-2
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发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
Akpan IJ
中科院分区：
文献类型：
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作者：
Cogan JC;Vianna PG;Akpan IJ
一名62岁的男性，艾滋病病毒感染得到很好的控制，于2016年12月到哥伦比亚大学医学中心(美国纽约州纽约)就诊，伴有进行性疲劳。他的血红蛋白浓度为5.0g/dL，并有溶血性贫血的实验室证据。多特异性直接抗体检测(DAT；也称为库姆斯直接检测)为阴性。对外周血片的评估揭示了图中所示的发现。他的家庭药物包括他的艾滋病毒抗逆转录病毒治疗，以及甲氧普林-磺胺甲恶唑(每周三次口服160毫克和800毫克)
A 62-year-old man with well-controlled HIV infection presented to Columbia University Medical Center (New York, NY, USA) in December, 2016, with progressive fatigue. He was found to have a haemoglobin con centration of 5· 0 g/dL, with laboratory evidence of haemolytic anaemia. Polyspecific direct antibody testing (DAT; also known as direct Coombs testing) was negative. Evaluation of a peripheral blood film revealed the findings presented in the figure. His home medications included his HIV anti-retroviral therapy, along with trimethoprim-sulfamethoxazole (160 mg and 800 mg orally three times a week) for