Acute Complete Heart Block in Dogs
Acute Complete Heart Block in Dogs
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狗的急性完全性心脏传导阻滞
DOI：
10.1161/01.cir.12.1.82
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发表时间：
1955
期刊：
影响因子：
37.8
通讯作者：
R. Baker
中科院分区：
文献类型：
--
作者：
Thomas E. Starzl;Robert A. Gaertner;R. Baker
在犬中手术产生完全心脏传导阻滞后立即和长达18天进行了一项研究。术后即刻，心输出量、冠状动脉流量和平均动脉压与心动过缓的程度大致成比例地降低。随着时间的推移，这些指标开始恢复到术前水平。左心室作功减少的另一个原因是左心室耗氧量减少，心肌效率几乎没有变化。检测到中心静脉压小幅升高。尸检时，唯一明确的异常是心肌肥大，在术后2 - 18天可测量。
A study has been conducted immediately and up to 18 days after the surgical production of complete heart block in dogs. Immediately after surgery cardiac output, coronary flow, and mean arterial pressure were reduced in rough proportion to the degree of bradycardia. In time, these measures began to return toward preoperative levels. Paralleling the diminished left ventricular work was a diminished left ventricular oxygen consumption with little consequent change in myocardial efficiency. Small rises were detected in central venous pressure. At autopsy, the only unequivocal abnormality was myocardial hypertrophy which became measurable between 2 and 18 days after operation.