Developmental aspects of the endocrine pancreas.
Developmental aspects of the endocrine pancreas.
复制标题
内分泌胰腺的发育方面。
DOI：
10.1023/a:1021809917576
复制
发表时间：
2003
影响因子：
8.2
通讯作者：
Habener,JoelF
中科院分区：
文献类型：
--
作者：
Kemp,DanielM;Thomas,MelissaK;Habener,JoelF
A detailed morphological map of pancreatic development has evolved over many years of careful observation of embryonic growth, particularly in the mouse, providing a template for the more challenging feat of identifying the developmental pathways in the pancreas at the molecular level. Definition of the mechanisms that regulate pancreatic growth and the differentiation of the endocrine and exocrine cell lineages during embryonic development may yield a better understanding of the molecular determinants of diseases such as diabetes. These answers also may facilitate a more educated approach in generating viable islet cell lines from adult and embryonic cells for transplantation.
