HIV providers' perceived barriers and facilitators to implementing pre-exposure prophylaxis in care settings: a qualitative study.
HIV providers' perceived barriers and facilitators to implementing pre-exposure prophylaxis in care settings: a qualitative study.
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DOI：
10.1007/s10461-014-0839-3
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发表时间：
2014-09
影响因子：
4.4
通讯作者：
Mayer, Kenneth H.
中科院分区：
文献类型：
--
作者：
Krakower, Douglas;Ware, Norma;Mitty, Jennifer A.;Maloney, Kevin;Mayer, Kenneth H.
口服暴露前预防（PrEP）可减少高危人群中的艾滋病毒发病率。然而，要使预防措施对降低艾滋病毒发病率产生影响，临床医生需要愿意开预防措施。艾滋病毒专家在使用抗逆转录病毒药物方面经验丰富，可以随时提供预防措施，但可能不照顾未感染艾滋病毒的患者。2012年5月至6月，由39名波士顿地区HIV护理提供者组成的6个焦点小组进行了评估，以评估处方PrEP的感知障碍和促进因素。参与者阐述了后勤和理论障碍，例如对现实环境中PrEP有效性的担忧，潜在的意外后果（例如风险解除抑制和药物毒性），以及认为PrEP在初级保健诊所提供更可行。他们确定了几个促成PrEP处方的因素，包括患者动机和规范性指南。总的来说，参与者报告了有限的处方意图。如果不采取干预措施解决艾滋病毒提供者的关切，在艾滋病毒诊所实施预防措施可能会受到限制。
Oral pre-exposure prophylaxis (PrEP) can reduce HIV incidence among at-risk persons. However, for PrEP to have an impact in decreasing HIV incidence, clinicians will need to be willing to prescribe PrEP. HIV specialists are experienced in using antiretroviral medications, and could readily provide PrEP, but may not care for HIV-uninfected patients. Six focus groups with 39 Boston-area HIV care providers were conducted (May-June 2012) to assess perceived barriers and facilitators to prescribing PrEP. Participants articulated logistical and theoretical barriers, such as concerns about PrEP effectiveness in real-world settings, potential unintended consequences (e.g. risk disinhibition and medication toxicity), and a belief that PrEP provision would be more feasible in primary care clinics. They identified several facilitators to prescribing PrEP, including patient motivation and normative guidelines. Overall, participants reported limited prescribing intentions. Without interventions to address HIV providers’ concerns, implementation of PrEP in HIV clinics may be limited.
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影响因子：
11.8
作者：
Karris, Maile Y.;Beekmann, Susan E.;Polgreen, Philip M.
通讯作者：
Polgreen, Philip M.
影响因子：
3.2
作者：
Hsieh, HF;Shannon, SE
通讯作者：
Shannon, SE
影响因子：
168.9
作者：
Choopanya, Kachit;Martin, Michael;Vanichseni, Suphak
通讯作者：
Vanichseni, Suphak
影响因子：
158.5
作者：
Thigpen, Michael C.;Kebaabetswe, Poloko M.;Brooks, John T.
通讯作者：
Brooks, John T.
DOI：
10.1097/qai.0b013e31818d5a27
发表时间：
2009-01-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Mimiaga MJ;Case P;Johnson CV;Safren SA;Mayer KH
通讯作者：
Mayer KH