Explaining the role of sex on disability: a population-based study.
Explaining the role of sex on disability: a population-based study.
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解释性别对残疾的作用：一项基于人口的研究。
DOI：
10.1093/geront/41.4.499
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Blaum,CS
中科院分区：
文献类型：
--
作者：
Wray,LA;Blaum,CS
目的：关于性别如何影响普遍的残疾以及通过什么机制影响残疾，目前还没有明确的共识。我们调查了性别是否对残疾有直接的独立影响，或者性别是否对慢性疾病/条件和残疾之间的关系有互动影响，以及这些影响在中年和老年人中是否不同。设计和方法：我们使用了两项具有全国代表性的健康访谈调查的基线数据，即健康与退休研究（HRS）和老年人资产与健康动态研究（AHEAD），以及两项调查中几乎相同的残疾和协变量测量。Logistic回归模型检验了疾病、损伤、人口统计学和社会特征对普遍的日常生活活动（ADLs）、流动性和力量困难的影响。结果：在调整关键协变量后，模型显示两个年龄组的ADL残疾没有直接的性别影响。然而，性别确实通过肌肉骨骼状况和抑郁症状对老年人ADL残疾产生间接影响。相比之下，在两个年龄组中，除去协变量，女性性别仍然与活动能力和力量残疾密切相关。主要的相互作用也很重要，包括女性性别/身体质量指数（BMI）对行动困难的相互作用和中年组中力量残疾的几种性别疾病的相互作用。意义：性别对ADL困难的影响在很大程度上可以通过社会和健康相关的协变量来解释。相比之下，女性性别与两组中力量和活动能力下降的独立关联不能用我们模型的社会或健康相关变量来解释。此外，女性的身体质量指数与行动困难的正相关程度明显低于男性。
Purpose:There is no clear consensus about how sex influences prevalent disability and through what mechanisms. We investigated whether sex had a direct inde-pendent effect on disability or whether sex had an interactive effect on the relationship between chronic diseases/conditions and disability, and whether these effects differed in middle-aged versus older adults.Design and Methods:We used baseline data from two nationally representative health interview surveys, the Health and Retirement Study (HRS) and the Study of Asset and Health Dynamics Among the Oldest Old (AHEAD), and disability and covariate measures that were nearly identical in both surveys. Logistic regression models tested the contributions of diseases, impairments, and demographic and social characteristics on difficulties with prevalent activities of daily living (ADLs), mobility, and strength.Results:Models demonstrated no direct sex effect for ADL disability in either age group after adjusting for key covariates. However, sex did exert an indirect effect on ADL disability in older adults via musculoskeletal conditions and depressive symptoms. In contrast, female sex remained strongly associated with mobility and strength disability in both age groups, net of covariates. Major interactions were also significant, including a female sex/body mass index (BMI) interaction for mobility difficulty and several sex–disease interactions for strength disability in the middle-aged group.Implications:The effect of sex on ADL difficulty is largely explained by social and health-related covariates in middle-aged and older adults. In contrast, the independent association of female sex with decreased strength and mobility in both groups cannot be explained by our models' social or health-related variables. In addition, the positive association of BMI with mobility difficulty is significantly worse for women than for men.
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种族和性别
DOI：
--
发表时间：
1988
期刊：
影响因子：
--
作者：
C. Husbands
通讯作者：
C. Husbands
影响因子：
5.4
作者：
VERBRUGGE, LM;JETTE, AM
通讯作者：
JETTE, AM
影响因子：
12.7
作者：
BRUCE, ML;SEEMAN, TE;BLAZER, DG
通讯作者：
BLAZER, DG
DOI：
10.1111/j.1532-5415.1994.tb07483.x
发表时间：
1994-04-01
影响因子：
6.3
作者：
GALANOS, AN;PIEPER, CF;FILLENBAUM, GG
通讯作者：
FILLENBAUM, GG
DOI：
10.1093/geronb/52b.special_issue.1
发表时间：
1997-05-01
影响因子：
6.2
作者：
Soldo, BJ;Hurd, MD;Wallace, RB
通讯作者：
Wallace, RB