Mitochondrial DNA control region variation from samples of the Moroccan population

Mitochondrial DNA control region variation from samples of the Moroccan population
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DOI:
10.1007/s00414-012-0813-4
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发表时间:
2013-07-01
影响因子:
2.1
通讯作者:
Amzazi, Saaid
Amzazi, Saaid
中科院分区:
医学3区
文献类型:
--
作者:
Aboukhalid, Rachid;Sturk-Andreaggi, Kimberly;Amzazi, Saaid

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为了促进摩洛哥法医线粒体DNA (mtDNA)测试,使用综合处理和数据审查系统生成了来自509个人的高质量控制区序列。这个来自不同摩洛哥人口群体(说阿拉伯语、说柏柏尔语和说撒哈拉语)的随机样本的大数据集显示出低随机匹配概率(0.52%),两两比较的平均值为13.24。这里研究的摩洛哥mtDNA基因库完全由西欧亚(58.15%)和非洲单倍群(41.85%)定义。
In an effort to facilitate forensic mitochondrial DNA (mtDNA) testing in Morocco, high-quality control region sequences from 509 individuals were generated using a comprehensive processing and data review system. This large dataset of random samples from various Moroccan population groups (Arab speaking, Berber speaking, and Sahrawi speaking) exhibited a low random match probability (0.52 %) and a mean of pairwise comparisons of 13.24. The Moroccan mtDNA gene pool studied here was defined entirely by West Eurasian (58.15 %) and African haplogroups (41.85 %).