HEMATOGENOUS CANDIDA ENDOPHTHALMITIS IN PATIENTS RECEIVING PARENTERAL-HYPERALIMENTATION FLUIDS
HEMATOGENOUS CANDIDA ENDOPHTHALMITIS IN PATIENTS RECEIVING PARENTERAL-HYPERALIMENTATION FLUIDS
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DOI：
10.1093/infdis/143.5.655
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发表时间：
1981-01-01
影响因子：
6.4
通讯作者：
MONTGOMERIE, JZ
中科院分区：
文献类型：
--
作者：
HENDERSON, DK;EDWARDS, JE;MONTGOMERIE, JZ
为了确定给予肠外高营养液的重症患者中血源性念珠菌性眼内炎的发生率，前瞻性评价了131例术后高营养患者。所有患者每周筛查一次脉络膜视网膜病变，血培养C。白色念珠菌和念珠菌感染的体征和症状。131例患者中有13例（9.9%）发生了与血源性念珠菌性眼内炎相容的脉络膜视网膜病变。13例眼部病变患者中有7例血培养酵母菌阳性; 118例无眼部病变患者中有2例血培养酵母菌阳性（P < 0.0005）。与血源性念珠菌性眼内炎一致的眼部病变的发生与酵母菌血培养阳性相关，强烈提示侵袭性念珠菌病。
To determine the incidence of hematogenous Candida endophthalmitis in seriously ill patients given parenteral hyperalimentation fluids, 131 hyperalimented postoperative patients were prospectively evaluated. All patients were screened weekly for the development of chorioretinal lesions, blood cultures positive for C. albicans and signs and symptoms of Candida infection. Thirteen (9.9%) of 131 patients developed chorioretinal lesions compatible with hematogenous Candida endophthalmitis. Seven of the 13 patients with eye lesions had blood cultures positive for yeast; 2 of 118 without eye lesions had blood cultures positive for yeast (P < 0.0005). The occurrence of eye lesions consistent with hematogenous Candida endophthalmitis correlated with positive blood cultures for yeast and strongly suggested invasive candidiasis.