SOURCES AND INTRACEREBRAL DISTRIBUTION OF AUDITORY EVOKED-POTENTIALS IN ALERT RHESUS-MONKEY
SOURCES AND INTRACEREBRAL DISTRIBUTION OF AUDITORY EVOKED-POTENTIALS IN ALERT RHESUS-MONKEY
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DOI：
10.1016/0006-8993(75)90682-4
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发表时间：
1975-01-01
期刊：
影响因子：
2.9
通讯作者：
VAUGHAN, HG
中科院分区：
文献类型：
--
作者：
AREZZO, J;PICKOFF, A;VAUGHAN, HG
在警觉的恒河猴中，从长期植入的电极记录了对点击刺激的平均听觉诱发电位（AEP）。每一个AEP成分的皮质来源被确定的基础上，经皮质极性反转。活动位点仅限于颞上平面（STP）和中央前运动皮层内的一个区域。在外侧上级颞回产生小的和不稳定的反应，在额叶颗粒皮层没有检测到本地产生的活动。STP的反应是复杂的，早期成分主要产生于听觉koniocortex和周围地区的后来的组件。这些成分中的每一个都是广泛的体积传导，在STP的上方和下方，并且它们投射到背外侧表面皮层的各个区域。来自STP的体积传导电位与运动皮层中产生的电位相加以产生复杂的合成波形。巴比妥类麻醉废除了所有，但主要的AEP，并减少了体积进行的投影在皮质表面的这种反应。将猴AEP的结构和颅内分布与人脑内和头皮AEP记录进行比较。
Average auditory evoked potentials (AEP) to click stimuli were recorded from chronically implanted electrodes in alert rhesus monkeys. The cortical sources of each AEP component were identified on the basis of transcortical polarity inversions. The active loci were limited to the supratemporal plane (STP) and to a region within precentral motor cortex. Small and inconstant responses were generated in the lateral superior temporal gyrus and no locally generated activity was detected in frontal granular cortex. The responses from STP were complex, with early components generated mainly within auditory koniocortex and later components in surrounding regions. Each of these components was volume-conducted widely, both above and below the STP, and they projected onto various regions of dorsolateral surface cortex. The volume-conducted potentials from the STP summed with the potentials generated in motor cortex to produce a complex resultant waveform. Barbiturate anesthesia abolished all but the primary AEP and reduced the volume-conducted projection of this response at the cortical surface. The configuration and intracranial distribution of the monkey AEP were compared to human intracerebral and scalp AEP recordings.