Real-time surveillance of illicit drug overdoses using poison center data
Real-time surveillance of illicit drug overdoses using poison center data
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DOI：
10.1080/15563650902967404
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发表时间：
2009-07-01
影响因子：
3.3
通讯作者：
Friedman, Lee S.
中科院分区：
文献类型：
--
作者：
Friedman, Lee S.
背景资料。2006年初，政府和媒体消息来源报道，犯罪集团将芬太尼与海洛因混合。其次是海洛因过量和与鸦片有关的死亡增加。最近的芬太尼暴发表明，需要确定和建立有效和反应迅速的实时监测工具，以监测美国的药物过量情况。目标。在这项研究中，评估了来自伊利诺伊州的毒物呼叫中心数据，以确定这些数据是否可以检测到2006年初在伊利诺伊州发生的疫情，以及是否可以用于实时监控。方法：研究方法。在这项分析中，使用了两步法来分析潜在的与海洛因有关的电话。首先，对数据进行回顾分析，以确定是否发生了任何显著的时间变化，然后进行前瞻性分析，以模拟实时监视。结果。在2002至2007年间，共有1,565个与海洛因有关的潜在来电，2006年的来电比2005年增加了63.6%。在前瞻性分析中，主要模型将确定2006年3月的疫情。结论。如果有一个使用毒物中心数据的实时监测计划，疫情就会在2006年4月底向疾病控制和预防中心提交初步尸检报告的前一个月被发现。中毒中心的数据为比尸检数据来源更早的预警系统提供了可能性，因为报告通常在接触后几个小时内做出。毒物中心的数据可以有效地用于监测与海洛因相关的暴露。
Background. In early 2006, government and media sources reported that crime syndicates were mixing fentanyl with heroin. This was followed by an increase in heroin overdoses and opiate-related deaths. The most recent fentanyl outbreak illustrated the need for identifying and establishing effective and responsive real-time surveillance tools to monitor drug overdoses in the United States. Objective. In this study, poison call center data from Illinois were evaluated to determine whether the data could have detected the outbreak that occurred in Illinois in early 2006 and whether it could be used for real-time surveillance. Methods. For this analysis, a two-step approach was used to analyze potential heroin-related calls. First, the data were analyzed retrospectively to identify whether any significant temporal shifts occurred, then a prospective analysis was conducted to simulate real-time surveillance. Results. Between 2002 and 2007, there were a total of 1,565 potential heroin-related calls, and the calls increased by 63.6% in 2006 compared to 2005. In the prospective analysis, the principal model would have identified the outbreak in March 2006. Conclusions. If there had been a real-time surveillance program using poison center data, the outbreak would have been identified I month before the initial postmortem reports to the Centers for Disease Control and Prevention at the end of April 2006. Poison center data provide the potential for an earlier warning system than postmortem data sources, because the reports are usually made within hours of the exposure. Poison center data can be effectively used to monitor heroin-related exposures.