The influence of various substances on the gliding motility of Mycoplasma mobile 163K.
The influence of various substances on the gliding motility of Mycoplasma mobile 163K.
复制标题
各种物质对移动支原体163K滑行运动的影响。
DOI：
10.1099/00221287-133-11-3193
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
H. Kirchhoff
中科院分区：
文献类型：
--
作者：
B. Piper;R. Rosengarten;H. Kirchhoff
测试了各种物质的无毒浓度对支原体163K的滑行能力的影响。作用于核酸合成（丝裂霉素）、蛋白质合成（嘌呤霉素、氯霉素）、能量代谢（对氯脲苯甲酸酯、碘乙酸酯）以及与细胞质膜或收缩元素（白蛋白、胆固醇、EDTA、2-丙醇、普鲁蛋白、CaCl2、MgCl2、秋水仙素和KI）反应的化合物对运动有显著的抑制作用。表面活性化合物Triton X-100、Tego和SDS在一定浓度和孵育时间内显著提高了滑翔速度。结果表明，移动m.s mobile的运动依赖于功能性的细胞质膜，并且细胞骨架元件参与了滑动机制。
Non-toxic concentrations of various substances were tested for their influence on the gliding motility of Mycoplasma mobile 163K. A significant inhibitory effect on motility was observed with agents acting on nucleic acid synthesis (mitomycin), protein synthesis (puromycin, chloramphenicol), energy metabolism (p-chloromercuribenzoate, iodoacetate) and with compounds reacting with the cytoplasmic membrane or contractile elements (albumin, cholesterol, EDTA, 2-propanol, procain, CaCl2, MgCl2, colchicin and KI). The surface-active compounds Triton X-100, Tego and SDS increased the gliding velocity significantly in some concentrations and incubation periods. The results suggest that the motility of M. mobile depends on a functional cytoplasmic membrane and that cytoskeletal elements are involved in the gliding mechanism.