Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma
Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma
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DOI：
10.1016/s1286-4579(03)00114-x
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发表时间：
2003-07-01
影响因子：
5.8
通讯作者：
Del Prete, G
中科院分区：
文献类型：
--
作者：
D'Elios, MM;Amedei, A;Del Prete, G
宿主T细胞对幽门螺杆菌的反应对于感染的临床结果是重要的。Th 1极化反应，优先针对Ca-A。与消化性溃疡相关，而混合Th 1和Th 0反应存在于非溃疡性胃炎。一个放松管制的H.幽门驱动的Th 0细胞依赖性B细胞活化见于粘膜相关淋巴组织的低度B细胞淋巴瘤。(C)2003年，Elsevier SAS科学与医学版。All rights reserved.
Host T-cell response to Helicobacter pylori is important for the clinical outcome of the infection. A Th1-polarized response, preferentially against Ca-A. is associated with peptic ulcer, whereas mixed Th1 and Th0 responses are present in non-ulcer gastritis. A deregulated H. pylori-driven Th0 cell-dependent B-cell activation is found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.