Nanoparticles in medicine: Therapeutic applications and developments
Nanoparticles in medicine: Therapeutic applications and developments
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DOI：
10.1038/sj.clpt.6100400
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发表时间：
2008-05-01
影响因子：
6.7
通讯作者：
Farokhzad, O. C.
中科院分区：
文献类型：
--
作者：
Zhang, L.;Gu, F. X.;Farokhzad, O. C.
纳米技术是对1-100 nm尺寸范围内物质的理解和控制。纳米技术在医学上的应用，被称为纳米医学，涉及使用这种长度尺度的精确工程材料来开发新的治疗和诊断方式。（1，2）纳米材料具有独特的物理化学性质，如超小尺寸、大表面积与质量比、高反应活性等，这些都不同于相同组成的块体材料。这些特性可用于克服在传统治疗和诊断剂中发现的一些局限性。
Nanotechnology is the understanding and control of matter generally in the 1-100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities.(1,2) Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents.