Sociodemographic, mental health, and physical health factors associated with participation within re-contactable mental health cohorts: an investigation of the GLAD Study.
Sociodemographic, mental health, and physical health factors associated with participation within re-contactable mental health cohorts: an investigation of the GLAD Study.
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DOI：
10.1186/s12888-023-04890-x
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发表时间：
2023-07-26
期刊：
影响因子：
4.4
通讯作者：
中科院分区：
文献类型：
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焦虑和抑郁的遗传联系（GLAD）研究是一个大型的终身焦虑和/或抑郁个体队列，旨在促进参与者的重新联系，以进行心理健康研究。在大流行开始时，包括GLAD研究在内的三个队列的参与者被邀请加入COVID-19精神病学和神经遗传学（COPING）研究，以监测精神和神经健康。然而，以前的研究表明，参与纵向研究遵循一个系统的，而不是随机的过程，这最终可能会导致结果的偏差。因此，本研究评估了GLAD研究参与者重新联系后的参与偏倚。2020年4月，所有目前的GLAD研究参与者（N = 36，770）被邀请参加COPING研究。使用逻辑回归，我们调查是否社会人口，心理和身体健康特征与参与COPING基线调查（目标一）。随后，我们使用零膨胀负二项回归来检验这些因素是否也与参与COPING后续调查有关（目标二）。对于目标一，年龄较大，女性性别认同，非二元或自我定义的性别认同，有一种或多种身体健康疾病，并为GLAD研究提供唾液试剂盒与完成COPING基线调查的几率增加相关。相比之下，较低的教育程度，亚裔或亚裔英国人的种族认同，黑人或黑人英国人的种族认同，在GLAD注册调查中较高的酒精消费量，以及当前或以前吸烟与降低的几率有关。对于目标二，年龄较大，女性性别，唾液试剂盒的提供与更大的COPING后续调查完成。较低的教育程度，较高的酒精消费量在GLAD研究注册，前吸烟，和自我报告的注意力缺陷多动障碍有负相关。当重新联系GLAD研究志愿者时，围绕社会人口统计学和身体健康特征的参与偏见尤其明显。与参与相关的因素可能因研究设计而异。研究人员应该研究参与偏见背后的障碍和机制，以解决这些问题，并在未来的研究中解决招聘偏见。 在线版本包含补充材料，可通过10.1186/s12888-023-04890-x获得。
The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed to facilitate re-contact of participants for mental health research. At the start of the pandemic, participants from three cohorts, including the GLAD Study, were invited to join the COVID-19 Psychiatry and Neurological Genetics (COPING) study to monitor mental and neurological health. However, previous research suggests that participation in longitudinal studies follows a systematic, rather than random, process, which can ultimately bias results. Therefore, this study assessed participation biases following the re-contact of GLAD Study participants. In April 2020, all current GLAD Study participants (N = 36,770) were invited to the COPING study. Using logistic regression, we investigated whether sociodemographic, mental, and physical health characteristics were associated with participation in the COPING baseline survey (aim one). Subsequently, we used a zero-inflated negative binomial regression to examine whether these factors were also related to participation in the COPING follow-up surveys (aim two). For aim one, older age, female gender identity, non-binary or self-defined gender identities, having one or more physical health disorders, and providing a saliva kit for the GLAD Study were associated with an increased odds of completing the COPING baseline survey. In contrast, lower educational attainment, Asian or Asian British ethnic identity, Black or Black British ethnic identity, higher alcohol consumption at the GLAD sign-up survey, and current or ex-smoking were associated with a reduced odds. For aim two, older age, female gender, and saliva kit provision were associated with greater COPING follow-up survey completion. Lower educational attainment, higher alcohol consumption at the GLAD Study sign-up, ex-smoking, and self-reported attention deficit hyperactivity disorder had negative relationships. Participation biases surrounding sociodemographic and physical health characteristics were particularly evident when re-contacting the GLAD Study volunteers. Factors associated with participation may vary depending on study design. Researchers should examine the barriers and mechanisms underlying participation bias in order to combat these issues and address recruitment biases in future studies. The online version contains supplementary material available at 10.1186/s12888-023-04890-x.
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DOI：
10.3138/cpp.2020-049
发表时间：
2020-07-01
期刊：
Canadian Public Policy. Analyse De Politiques
影响因子：
--
作者：
Lemieux T;Milligan K;Schirle T;Skuterud M
通讯作者：
Skuterud M
影响因子：
5.2
作者：
Kekkonen, V.;Kivimaki, P.;Laukkanen, E.
通讯作者：
Laukkanen, E.
影响因子：
6.3
作者：
Angel Bellon, Juan;de Dios Luna, Juan;Torres-Gonzalez, Francisco
通讯作者：
Torres-Gonzalez, Francisco
影响因子：
3.3
作者：
Hansson, Isabelle;Berg, Anne Ingeborg;Thorvaldsson, Valgeir
通讯作者：
Thorvaldsson, Valgeir
影响因子：
4
作者：
May, Anne M.;Adema, Lotte E.;Peeters, Petra H. M.
通讯作者：
Peeters, Petra H. M.