Multidimensional smoker profiles and their prediction of smoking following a pharmacobehavioral intervention

Multidimensional smoker profiles and their prediction of smoking following a pharmacobehavioral intervention
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DOI:
10.1016/j.jsat.2007.08.006
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发表时间:
2008-07-01
影响因子:
3.9
通讯作者:
Buchkremer, Gerhard
Buchkremer, Gerhard
中科院分区:
医学2区
文献类型:
--
作者:
Batra, Anil;Collins, Susan E.;Buchkremer, Gerhard

文献摘要

被引文献

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这项观察性研究的目的是确定多维吸烟者特征,以帮助开发针对不同吸烟者亚型的未来定制治疗。根据文献中的发现,假设报告新奇寻求/多动、抑郁和尼古丁依赖水平较高的吸烟者在干预后吸烟的几率比报告这些方面症状水平较低的吸烟者更高。德国西南部的成年定期吸烟者(N=165)完成了自我报告问卷,评估了心理和吸烟变量,并接受了药物行为干预。K-均值聚类分析包括抑郁、寻求新奇/多动和尼古丁依赖等指标,证实了假设的吸烟者特征。这些聚类在交叉验证上表现出稳健性,并在随访中预测吸烟。具体地说,与得分低的吸烟者相比,抑郁、寻求新奇/过度活跃和较高依赖性特征的吸烟者在随访中吸烟的几率明显更高。(C)2008 Elsevier Inc.保留所有权利。
The objective of this observational study was to identify multidimensional smoker profiles to aid the development of future tailored treatments for different smoker subtypes. Based on findings in the literature, it was hypothesized that smokers reporting higher levels of novelty seeking/hyperactivity, depressivity, and nicotine dependence would evince greater odds of postintervention smoking than smokers reporting lower symptom levels across these dimensions. Adult regular smokers (N = 165) in southwest Germany completed self-report questionnaires assessing psychological and smoking variables and received a pharmacobehavioral intervention. A k-means cluster analysis involving indicators of depressivity, novelty seeking/hyperactivity, and nicotine dependence confirmed the hypothesized smoker profiles. These clusters evinced robustness on cross-validation and predicted smoking on follow-up. Specifically, smokers with depressive, novelty-seeking/hyperactive, and higher dependence profiles evinced significantly greater odds of smoking on follow-up than smokers with low-scoring profiles. (c) 2008 Elsevier Inc. All rights reserved.