Cardiovascular risk profile and outcome of patients with abdominal aortic aneurysm in out-patients with atherothrombosis: Data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry
Cardiovascular risk profile and outcome of patients with abdominal aortic aneurysm in out-patients with atherothrombosis: Data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry
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DOI：
10.1016/j.jvs.2008.05.026
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发表时间：
2008-10-01
影响因子：
4.3
通讯作者：
Bhatt, Deepak L.
中科院分区：
文献类型：
--
作者：
Baumgartner, Iris;Hirsch, Alan T.;Bhatt, Deepak L.
目的：关于腹主动脉瘤（AAA）患者的数据集几乎普遍局限于单个地理区域。我们的目的是在全球REACH（减少动脉粥样硬化血栓形成以持续健康）Registry.Methods中获得已知AAA的多种族患者的风险因素概况和心血管（CV）共病数据：REACH登记研究是一项国际性、前瞻性、观察性门诊患者登记研究，招募年龄2：45岁的门诊患者，这些患者患有确定的必然动脉疾病（CAD）、脑血管疾病（CVD）或外周动脉疾病（PAD）或至少有三种动脉粥样硬化血栓形成风险因素。本报告包括对44个国家68，236例门诊患者的观察结果。主要结果指标：性别、种族、CV风险因素、确诊动脉粥样硬化疾病比较了患有和不患有AAA的患者基线时的（CAD、CVD和PAD）以及1年时的CV结局事件。结果：在REACH登记研究入组的68，236例门诊患者中，1722例（2.5%）报告了所有AAA。年龄较大（73 +/- 8 vs 68 +/- 10，P < .0001），男性（81% vs 63%，P < .0001），白色种族（79% vs 67%，P < .0001），
Objective: Datasets regarding patients with abdominal aortic aneurysm (AAA) have almost universally, been restricted to single geographic regions. We aimed to obtain data oil the risk factor profile and cardiovascular (CV) co-morbidity among multi-ethnic patients with known AAA in the global REACH (REduction of Atherothrombosis for Continued Health) Registry.Methods: The REACH Registry is ail international, prospective, observational out-patient registry enrolling out-patients 2:45 years of age with established corollary artery disease (CAD), cerebrovascular disease (CVD) or peripheral arterial disease (PAD) or with at least three atherothrombotic risk factors. This report includes observations pertaining to 68,236 out-patients enrolled in 44 countries.Main outcome measures: Gender, ethnic origin, CV risk factors, established atherosclerotic disease (CAD, CVD and PAD) at baseline, and CV outcome events at 1-year were compared in patients with and without AAA.Results: Ail AAA was reported in 1722 (2.5%) of 68,236 out-patients enrolled in the REACH Registry. Older age (73 +/- 8 vs 68 +/- 10, P < .0001), male gender (81% vs 63%, P < .0001), White ethnicity (79% vs 67%, P