Racial and Ethnic Disparities in Hospitalizations and Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infections in the United States
Racial and Ethnic Disparities in Hospitalizations and Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infections in the United States
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DOI：
10.1016/j.annepidem.2011.03.002
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发表时间：
2011-08-01
影响因子：
5.6
通讯作者：
Finelli, Lyn
中科院分区：
文献类型：
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作者：
Dee, Deborah L.;Bensyl, Diana M.;Finelli, Lyn
目得：关于2009年甲型H1N1流感大流行（pH 1 N1）的疾病严重程度和对美国少数民族人口的健康后果可能存在种族-民族差异的担忧已经提出。使用来自疾病控制和预防中心行为风险因素监测系统、新发感染项目流感相关住院监测和流感相关儿科死亡率监测的数据，我们计算了种族-种族特异性、年龄调整后的自我报告的流感样疾病（ILI）和pH 1 N1相关住院率。我们使用卡方检验来评估ILI相关的就医行为和pH 1 N1住院治疗的种族-民族差异。为了评估儿科死亡，我们比较了种族，民族的死亡比例对美国人口distribution.RESULTS：自我报告的ILI的患病率较低的西班牙裔（6.5%），较高的美洲印第安人/阿拉斯加原住民（16.2%），和非西班牙裔黑人（7.7%）与非西班牙裔白人（8.5%）相比。在ILI相关的就医行为中没有发现种族-民族差异。与非西班牙裔白人（3.0/100，000）相比，所有少数民族人群（范围：8.1-10.9/100，000）中经调整的pH 1 N1相关新发感染计划住院率较高。pH 1 N1相关的儿科死亡的比例高于预期的西班牙裔（31%）和低于预期的非西班牙裔白人（45%）的美国人口的比例，他们组成（分别为22%和58%）。结论：种族种族差异的pH 1 N1相关的住院治疗和儿科死亡被确定。接种疫苗仍然是预防流感的主要干预措施。Ann Epidemiol 2011;21：623-630.爱思唯尔公司出版
PURPOSE: Concerns have been raised regarding possible racial-ethnic disparities in 2009 pandemic influenza A (H1N1) (pH1N1) illness severity and health consequences for U.S. minority populations.METHODS: Using data from the Centers for Disease Control and Prevention's Behavioral Risk Factor Surveillance System, Emerging Infections Program Influenza-Associated Hospitalization Surveillance, and Influenza-Associated Pediatric Mortality Surveillance, we calculated race-ethnicity-specific, age-adjusted rates of self-reported influenza-like illness (ILI) and pH1N1-associated hospitalizations. We used chi(2) tests to evaluate racial-ethnic disparities in ILI-associated health care-seeking behavior and pH1N1 hospitalization. To evaluate pediatric deaths, we compared racial-ethnic proportions of deaths against U.S. population distributions.RESULTS: Prevalence of self-reported ILI was lower among Hispanics (6.5%), higher among American Indians/Alaska Natives (16.2%), and similar among non-Hispanic blacks (7.7%) compared with non-Hispanic whites (8.5%). No racial-ethnic differences were identified in ILI-associated health care-seeking behavior. Age-adjusted pH1N1-associated Emerging Infections Program hospitalization rates were higher among all minority populations (range: 8.1-10.9/100,000 population) compared with non-Hispanic whites (3.0/100,000). The proportion of pH1N1-associated pediatric deaths was higher than expected among Hispanics (31%) and lower than expected among non-Hispanic whites (45%) given the proportions of the U.S. population they comprise (22% and 58%, respectively).CONCLUSIONS: Racial-ethnic disparities in pH1N1-associated hospitalizations and pediatric deaths were identified. Vaccination remains the primary intervention for preventing influenza. Ann Epidemiol 2011;21:623-630. Published by Elsevier Inc.