Obesity and health-related quality of life.
Obesity and health-related quality of life.
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DOI：
10.1046/j.1467-789x.2001.00032.x
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发表时间：
2001-08-01
期刊：
影响因子：
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通讯作者：
Barofsky, I
中科院分区：
文献类型：
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作者：
Fontaine, K R;Barofsky, I
虽然肥胖与发病率和死亡率密切相关，但肥胖对功能状态和健康相关生活质量（HRQL）的影响知之甚少。然而，近年来已经进行了研究，以估计肥胖对HRQL的影响，并确定减肥对HRQL的影响。大多数已发表的研究表明，肥胖会损害HRQL，并且肥胖程度越高，损害越大。与肥胖相关的HRQL下降往往是最明显的身体功能领域。肥胖手术对病态肥胖患者影响的研究表明，该手术对大多数HRQL指标产生了显著和持续的改善;在轻度至中度肥胖患者中，生活方式改变导致的适度体重减轻似乎也改善了HRQL，至少在短期内如此。需要进一步的研究来（1）进一步描述肥胖对HRQL的影响;（2）估计各种减肥方法的短期和长期影响（3）改进HRQL的概念化和测量，以纳入患者的个人偏好和价值观;（4）即使难以维持体重，也要设法提高和维持HRQL的积极变化。
Although it is well documented that obesity is strongly associated with morbidity and mortality, less is known about the impact of obesity on functional status and health-related quality of life (HRQL). However, in recent years research has been conducted to estimate the impact of obesity on HRQL, and to determine the effects of weight reduction on HRQL. The majority of published studies indicate that obesity impairs HRQL, and that higher degrees of obesity are associated with greater impairment. Obesity-associated decrements on HRQL tend to be most pronounced on physical domains of functioning. Studies of the effect of obesity surgery among morbidly obese patients indicate that this procedure produces significant and sustained improvements in the majority of HRQL indices; among mild-to-moderately obese persons, modest weight reduction derived from lifestyle modification also appears to improve HRQL, at least in the short term. Additional research is needed to (1) further characterize the effect that obesity has on HRQL; (2) estimate the short- and long-term effects of various methods of weight reduction (e.g. surgery, lifestyle modification) on HRQL; (3) improve both the conceptualization and measurement of HRQL to incorporate the personal preferences and values of the patient; and (4) develop ways to enhance and sustain positive changes in HRQL, even if weight maintenance is elusive.