Quality of life among survivors of early-stage cervical cancer in Taiwan: an exploration of treatment modality differences
Quality of life among survivors of early-stage cervical cancer in Taiwan: an exploration of treatment modality differences
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DOI：
10.1007/s11136-017-1619-0
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发表时间：
2017-10-01
影响因子：
3.5
通讯作者：
Chen, Lynn
中科院分区：
文献类型：
--
作者：
Li, Chia-Chun;Chang, Ting-Chang;Chen, Lynn
患有早期宫颈癌的女性可能会因为治疗或癌症的影响而改变生活质量（QoL）。在这项研究中，我们研究了仅接受手术治疗的妇女和接受同步放化疗（CCRT）治疗的妇女之间生活质量的差异。样本为290名被诊断为I-II期宫颈癌的妇女。分别使用作者设计的人口统计学疾病调查、欧洲癌症研究与治疗组织生活质量问卷和台湾版宫颈癌模块24问卷收集这些妇女的人口统计学和疾病特征、一般生活质量和癌症特异性生活质量的数据。资料以描述性统计及协方差分析进行分析，结果发现单纯手术治疗的子宫颈癌患者便秘及身体形象明显较接受连续性放疗者差。接受CCRT的女性比仅接受手术的女性有更差的身体和角色功能。接受CRRT的妇女也报告了更严重的症状，如疲劳，食欲不振，腹泻，经济困难，性享受，性/阴道功能，比那些只接受手术的妇女，我们的研究结果增加了对接受不同治疗方式的早期宫颈癌妇女生活质量的了解。当建议宫颈癌妇女的治疗方式时，卫生专业人员还应考虑癌症治疗后妇女生活质量的变化。为了提高妇女治疗后的生活质量，专业人员还应根据妇女的宫颈癌治疗提供及时和个性化的干预。
Women with early-stage cervical cancer may experience changes in their quality of life (QoL) due to treatment or to the effects of the cancer. In this study, we examined differences in QoL by treatment modality between women who underwent surgery only and those treated with concurrent chemoradiation (CCRT).The sample of 290 women had been diagnosed with stage I-II cervical cancer. Data were collected on these women's demographic and disease characteristics, general QoL, and cancer-specific QoL using an author-designed demographic-disease survey, the European Organization for Research and Treatment of Cancer QoL questionnaire, and the Taiwanese-version Cervical Cancer Module 24 questionnaire, respectively. Data were analyzed by descriptive statistics and analysis of covariance.Women with cervical cancer who underwent surgery only had significantly worse constipation and body image than those treated with CCRT. Women who underwent CCRT had worse physical and role functioning than those who underwent surgery only. Women who had CCRT also reported worse symptoms, such as fatigue, appetite loss, diarrhea, financial difficulties, sexual enjoyment, and sexual/vaginal functioning, than those who had only surgery.Our results add knowledge about QoL in women with early-stage cervical cancer who receive different treatment modalities. When suggesting treatment modalities for women with cervical cancer, health professionals should also consider changes in women's QoL after cancer treatment. To improve women's QoL after treatment, professionals should also offer timely and individualized interventions based on women's cervical cancer treatment.