Epileptic seizures: Quakes of the brain?
Epileptic seizures: Quakes of the brain?
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DOI：
10.1103/physreve.82.021919
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发表时间：
2010-08-20
影响因子：
2.4
通讯作者：
Lai, Ying-Cheng
中科院分区：
文献类型：
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作者：
Osorio, Ivan;Frei, Mark G.;Lai, Ying-Cheng
五种无标度统计数据（事件大小的古登堡 - 里希特分布、事件间隔分布、大森定律和逆大森定律，以及到下一次事件的条件等待时间）所支持的一种动力学类比，被证明存在于两类癫痫发作（人类的“局灶性”发作和动物的全身性发作）与地震之间。动物中兴奋性中间神经元耦合的增加揭示了系统对该参数的依赖性及其动力学可变性：适度增加导致癫痫发作能量和事件间隔时间呈现幂律行为，而显著增加则导致与特征尺度和事件共存的无标度（幂律）行为。幂律和特征尺度区域的共存性由耦合的弛豫异质阈值振子模型预测，并强调了耦合强度在塑造这些系统动力学方面的作用。
A dynamical analogy supported by five scale-free statistics (the Gutenberg-Richter distribution of event sizes, the distribution of interevent intervals, the Omori and inverse Omori laws, and the conditional waiting time until the next event) is shown to exist between two classes of seizures ("focal" in humans and generalized in animals) and earthquakes. Increments in excitatory interneuronal coupling in animals expose the system's dependence on this parameter and its dynamical transmutability: moderate increases lead to power-law behavior of seizure energy and interevent times, while marked ones to scale-free (power-law) coextensive with characteristic scales and events. The coextensivity of power law and characteristic size regimes is predicted by models of coupled heterogeneous threshold oscillators of relaxation and underscores the role of coupling strength in shaping the dynamics of these systems.