Indium trichloride-mediated facile synthesis of 3-(substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole in water
Indium trichloride-mediated facile synthesis of 3-(substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole in water
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DOI：
10.1002/cjoc.200690235
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发表时间：
2006-09-01
影响因子：
5.4
通讯作者：
Hu De-Yu
中科院分区：
文献类型：
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作者：
Yang Song;Liu Jie;Hu De-Yu
在三氯化铟的催化下，3-(取代methylthio)-4-phenyl-5(3，4，5-trimethoxyphenyl)-4H-1，2，4-triazole)与不同卤化物在水相介质中发生高产率反应，得到了一种环境友好、高效的3-取代4-phenyl-5-(3，4，5-trimedioxyphenyl)4H-1，2，4-triazole-3-thiol合成工艺。
An environmentally benign and efficient process for the preparation of 3-(substituted methylthio)-4-phenyl-5(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole was achieved by the reaction of 4-phenyl-5-(3,4,5-trimedioxyphenyl)4H-1,2,4-triazole-3-thiol with different halides in aqueous media mediated by indium trichloride in high yields.