A genetic method for determining the order of events in a biological pathway.

A genetic method for determining the order of events in a biological pathway.
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一种确定生物途径中事件顺序的遗传方法。

DOI:
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发表时间:
1973
影响因子:
11.1
通讯作者:
D. Botstein
D. Botstein
中科院分区:
综合性期刊1区
文献类型:
--
作者:
J. Jarvik;D. Botstein

文献摘要

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我们描述了一个简单的基因测试的应用,表明在形态发生或生化途径事件的顺序。该测试使用温度敏感(ts)和冷敏感(cs)突变体,并对ts和cs缺陷表达的时间进行排序。
We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which the ts and cs defects are expressed.