Laparoscopic left lateral section procurement in living liver donors: A single center propensity score-matched study
Laparoscopic left lateral section procurement in living liver donors: A single center propensity score-matched study
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DOI：
10.1111/ctr.13374
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发表时间：
2018-09-01
影响因子：
2.1
通讯作者：
Chekletsova, Elena
中科院分区：
文献类型：
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作者：
Gautier, Sergey;Monakhov, Artem;Chekletsova, Elena
背景：在过去的十年中，腹腔镜活体供肝移植越来越受欢迎。本研究的目的是比较腹腔镜和开放入路在活体供体左外侧切除术（LLS）中的应用，并评估腹腔镜入路的安全性和可行性。方法：2016年5月至2017年12月在我中心共进行103例活体供体lss手术。其中，35例是完全的腹腔镜手术，这代表了本研究的主题。在同一时期进行的另外68例开放活体供体lss作为对照组进行研究。为了克服选择偏倚，根据具有相似值的协变量，以1:1的比例（腹腔镜[n = 35]：开放[n = 35]）平衡LLS供体。PSM是基于手术日期、受者年龄、诊断、受者体重和供者年龄。结果：腹腔镜组与开放组在失血量（96.8 +/- 16.5 mL vs 155.8 +/- 17.8 mL）和住院时间（4 +/- 0.4 d vs 6.9 +/- 0.5 d）方面差异有统计学意义（P < 0.001）。结论：在先进的腹腔镜专业技术下，腹腔镜下的LLS是一种可行且有效的方法。
Background: Laparoscopic living donor liver procurement for transplantation has increased in popularity over the past decade. The purpose of this study was to compare the laparoscopic and open approaches in living donor left lateral sectionectomy (LLS) and to assess the safety and feasibility of this laparoscopic approach.Methods: A total of 103 living donor LLSs were performed at our center from May 2016 to December 2017. Of these, 35 were completely laparoscopic procedures, which represented the subject of this study. An additional 68 open living donor LLSs performed during the same period were studied as a comparison group. To overcome selection bias, LLS donors were balanced on a 1:1 ratio (laparoscopic [n = 35]: open [n = 35]) according to covariates with similar values. The PSM was based on the operation date, recipient age, diagnosis, recipient weight, and donor age.Results: There were significant differences between the laparoscopic and open LLS groups (P < 0.001) in terms of blood loss (96.8 +/- 16.5 vs 155.8 +/- 17.8 mL) as well as the duration of hospital stay (4 +/- 0.4 vs 6.9 +/- 0.5 days).Conclusion: Laparoscopic LLS is a feasible and efficacious in the setting of a developed program with advanced laparoscopic expertise.