Thallium-201 myocardial imaging: a comparison of the redistribution and rest images.

Thallium-201 myocardial imaging: a comparison of the redistribution and rest images.
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铊 201 心肌成像:再分布图像和静止图像的比较。

DOI:
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发表时间:
1979
影响因子:
9.3
通讯作者:
G. Hamilton
G. Hamilton
中科院分区:
医学1区
文献类型:
--
作者:
J. Ritchie;P. Albro;J. Caldwell;G. Trobaugh;G. Hamilton

文献摘要

被引文献

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对41例有胸痛和可疑冠状动脉疾病的患者进行了Tl-201心肌显像,分别在极量平板运动后即刻、运动后4~5小时的“再分配”时和运动后1周后的休息时进行。所有患者均行冠状动脉造影术。7例无冠状动脉病变的患者所有图像均正常。在34名冠心病患者中,有27名(79%)出现了新的运动导致的图像缺陷。15/27(56%)患者(完全再分布)的再分布图像与静止图像相同。27例运动性运动缺陷者中,10例(37%)出现了一定程度的再分布,但再分布图像上的缺陷大小大于静止图像上的大小(不完全再分布)。在2/27(7%)的运动性缺陷患者中,没有重新分布。既往有心肌梗死史、左心室局部收缩异常或冠状动脉狭窄的严重程度与有无再分布无关。两项研究的总体图像质量相似,尽管重新分配研究的图像收集时间延长了。我们得出的结论是,在大多数运动性图像缺陷患者中,会发生一些重分布(完全或不完全)。当同时存在固定的和可逆的灌注缺损区时,再分布图像上的缺损区大小往往较大,因此可能高估了先前心肌梗死的范围。
Forty-one patients with chest pain and suspected coronary artery disease underwent thallium-201 myocardial imaging, performed immediately following maximal treadmill exercise, also at "redistribution" 4--5 hr after exercise, and at rest 1 wk later. All had coronary angiography. All images in seven patients without coronary artery disease were normal. Twenty-seven of the 34 (79%) patients with coronary artery disease had new, exercise-induced image defects. The redistribution and rest images were identical in 15/27 (56%) patients (complete redistribution). In 10/27 (37%) patients with exercise-induced defects, some redistribution occurred but defect size on the redistribution image was larger than that on the rest images (incomplete redistribution). In 2/27 (7%) of patients with exercise-induced defects, redistribution was absent. The presence of prior myocardial infarction, regional abnormalities of left-ventricular contraction or the severity of coronary stenoses did not correlate with the presence or absence of redistribution. Overall image quality between the two studies was similar, although image collection times for the redistribution study were prolonged. We conclude that some redistribution (complete or incomplete) occurs in most patients with exercise-induced image defects. When both fixed and reversible perfusion defects are present, defect size was often larger in the redistribution image and may thus overestimate the extent of prior myocardial infarction.