A Model of Adolescent Sleep Health and Risk for Type 2 Diabetes.

A Model of Adolescent Sleep Health and Risk for Type 2 Diabetes.
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DOI:
10.1007/s11892-020-01373-1
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发表时间:
2021-01-15
影响因子:
4.2
通讯作者:
Nadeau KJ
Nadeau KJ
中科院分区:
医学2区
文献类型:
--
作者:
Simon SL;Higgins J;Melanson E;Wright KP Jr;Nadeau KJ

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本文回顾了目前的文献,以支持解释睡眠健康与青少年2型糖尿病风险之间关系的模型。睡眠时间短与年轻人患肥胖症的风险有关。睡眠限制会增加能量消耗,但也会增加饥饿感,食欲和食物摄入,导致能量平衡,影响食欲调节激素,并导致深夜进食增加。睡眠不足可能会导致身体活动减少和更多的久坐行为。此外,睡眠时间短与胰岛素敏感性降低有关。睡眠不足的累积负面后果会增加患2型糖尿病的风险。临床护理,公共政策和未来的研究应用进行了讨论。青春期睡眠不足直接通过影响胰岛素敏感性增加2型糖尿病的风险,间接通过增加饮食摄入,久坐活动和体重增加。
This paper presents a review of the current literature in support of a model explaining the relationships between sleep health and risk for type 2 diabetes in adolescents. Short sleep duration is associated with risk of developing obesity in youth. Sleep restriction increases energy expenditure, but also increases hunger, appetite, and food intake, causing positive energy balance, impacting appetite-regulating hormones, and leading to increased eating late at night. Insufficient sleep may lead to reduced physical activity and greater sedentary behaviors. In addition, short sleep duration is associated with reduced insulin sensitivity. The cumulative negative consequences of insufficient sleep increase risk for type 2 diabetes. Applications to clinical care, public policy, and future research are discussed. Insufficient sleep in adolescence increases risk for type 2 diabetes directly through impact on insulin sensitivity and indirectly through increased dietary intake, sedentary activity, and weight gain.
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