Self-assembly of Fmoc-diphenylalanine inside liquid marbles
Self-assembly of Fmoc-diphenylalanine inside liquid marbles
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DOI：
10.1016/j.colsurfb.2012.03.028
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发表时间：
2012-09-01
影响因子：
5.8
通讯作者：
Cardoso, Andre Zamith
中科院分区：
文献类型：
--
作者：
Braun, Hans-Georg;Cardoso, Andre Zamith
由Lycopodium clavatum孢子制成的液体大理石用于封装9-芴基甲氧羰基-二苯基丙氨酸（Fmoc-FF）的水溶液。Fmoc-FF溶液在液体大理石的液体/空气界面处的酸化触发带状肽原纤维自组装成肽膜（50-500 nm）。该膜结合石松微粒，并因此稳定的液体大理石对崩溃，否则可能会发生通过在浮动interphase.Ultrathin纳米结构的肽膜形成在液体/空气界面内也观察到人工微结构的浮动物体。因此，通过SEM和TEM检查形成的肽膜。电子衍射数据揭示了寡肽膜内分子组织的信息。(C)2012爱思唯尔有限公司版权所有。
Liquid marbles made from Lycopodium clavatum spores are used to encapsulate aqueous solutions of 9-fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF). Acidification of the Fmoc-FF solution at the liquid/air interface of the liquid marble triggers the self-assembly of ribbon-like peptide fibrils into an ultrathin peptide membrane (50-500 nm). The membrane incorporates the lycopodium microparticles and as a result stabilizes the liquid marble against collapse, that could otherwise occur through particle disintegration at the floating interphase.Ultrathin nanostructured peptide membrane formation at the liquid/air interface is also observed within artificial microstructured floating objects. Thus, peptide membranes formed were inspected by SEM and TEM. Electron diffraction data reveal information about the molecular organization inside the oligopeptide membranes. (C) 2012 Elsevier B.V. All rights reserved.