DISEASE-ACTIVITY INDEXES IN RHEUMATOID-ARTHRITIS - A PROSPECTIVE, COMPARATIVE-STUDY WITH THERMOGRAPHY
DISEASE-ACTIVITY INDEXES IN RHEUMATOID-ARTHRITIS - A PROSPECTIVE, COMPARATIVE-STUDY WITH THERMOGRAPHY
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DOI：
10.1136/ard.44.7.434
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发表时间：
1985-01-01
影响因子：
27.4
通讯作者：
HAZLEMAN, BL
中科院分区：
文献类型：
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作者：
DEVEREAUX, MD;PARR, GR;HAZLEMAN, BL
在类风湿关节炎的疾病活动性的评估有很多困难。红外热成像用于量化关节炎症。热分布指数（HDI）是可重复的，敏感的，可量化的，不受昼夜变化或观察者之间的错误。对肘、腕、膝和踝的HDI进行求和，并与疾病活动的其他参数进行比较。在20例典型的血清阳性类风湿关节炎患者中进行了167组观察，随访时间超过12个月。热像图与里奇关节指数、Mallaya评分、握力、晨僵、红细胞沉降率和疼痛评分显著相关（P < 0.001）。在个别患者中，热像图与这些参数显著相关（P < 0.05）。总结HDI是一个合适的，客观的方法来评估类风湿关节炎患者的治疗反应。
There are many difficulties associated with the assessment of disease activity in rheumatoid arthritis. Infrared thermography was used to quantify joint inflammation. The heat distibution index (HDI) was reproducible, sensitive, quantifiable and not subject to circadian variation or interobserver error. The HDI for both elbows, wrists, knees and ankles were summated and compared with other parameters of disease activity. There were 167 sets of observations in 20 patients with classical, seropositive, rheumatoid arthritis followed up over 12 mo. There was a significant correlation (P < 0.001) for thermography with the Ritchie articular index, Mallaya score, grip strength, morning stiffness, erythrocyte sedimentation rate and pain score. Significant correlations (P < 0.05) for thermography with these parameters were found in individual patients. The summated HDI is a suitable, objective method for the assessment of response to therapy in patients with rheumatoid arthritis.