Candida albicans adherence to resin-composite restorative dental material:: Influence of whole human saliva
Candida albicans adherence to resin-composite restorative dental material:: Influence of whole human saliva
复制标题
DOI：
10.1067/moe.2002.126024
复制
发表时间：
2002-11-01
期刊：
影响因子：
--
通讯作者：
Pontón, J
中科院分区：
文献类型：
--
作者：
Maza, JL;Elguezabal, N;Pontón, J
客观的。白色念珠菌附着在口腔表面被认为是口腔定植和念珠菌相关假牙口腔炎等口腔疾病发展的关键事件。尽管有关白色念珠菌与颊上皮细胞和修复材料粘附的信息相当多，但有关白色念珠菌与复合修复材料粘附的信息却很少。本研究的目的是研究白色念珠菌对树脂复合修复材料（Herculite）的粘附程度。方法。在将真菌和树脂在有或没有人全唾液的情况下孵育后，通过视觉方法研究了 2 株白色念珠菌（萌发突变体和芽管缺陷突变体）的粘附。结果。在没有唾液的情况下，白色念珠菌萌发分离株对树脂的粘附显示出与萌发平行的增加，在实验结束时（120分钟）达到最大值。然而，在研究期间，未观察到萌芽突变体的粘附存在显着差异。在唾液存在的情况下，两种分离株对树脂的粘附均显着降低。结论。发芽和人类全唾液的存在是白色念珠菌粘附到树脂复合修复材料 Herculite 上的重要因素。
Objective. Attachment of Candida albicans to oral surfaces is believed to be a critical event in the colonization of the oral cavity and in the development of oral diseases such as Candida-associated denture stomatitis. Although there is considerable information about the adhesion of C albicans to buccal epithelial cells and prosthetic materials, there is very little information about the adhesion of C albicans to composite restorative materials. The purpose of this study was to investigate the degree of adhesion of C albicans to a resin-composite restorative material (Herculite).Methods. The adhesion of 2 strains of C albicans, a germinative and a germ tube-deficient mutant, was studied by a visual method after incubating the fungus and the resin with and without human whole saliva.Results. In absence of saliva, the adhesion of the C albicans germinative isolate to the resin showed an increase in parallel with the germination, reaching a maximum at the end of the experiment (120 minutes). However, no significant differences were observed in the adhesion of the agerminative mutant during the period of time studied. In the presence of saliva, the adhesion of both isolates to the resin was significantly lowered.Conclusion. Germination and the presence of human whole saliva are important factors in the adhesion of C albicans to the resin-composite restorative material Herculite.