Small intestinal mucosal abnormalities in relatives of patients with dermatitis herpetiformis
Small intestinal mucosal abnormalities in relatives of patients with dermatitis herpetiformis
复制标题
疱疹样皮炎患者亲属小肠黏膜异常
作者：
J. Marks;D. Birkett;S. Shuster;D. Roberts
在19名疱疹样皮炎患者的亲属中进行了空肠活检，在7名患者中发现了立体显微镜异常。大多数发现这些异常的亲属没有肠道症状：一个有疱疹样皮炎皮疹。除了一个被发现小肠粘膜异常的亲属的先证者之外，其他人都患有腹腔综合征。它的结论是，遗传因素参与生产的肠病疱疹样皮炎在其他形式的腹腔综合征。
Jejunal biopsy has been carried out in 19 relatives of patients with dermatitis herpetiformis and stereomicroscopic abnormalities have been found in seven. The majority of the relatives in whom these abnormalities were found had no bowel symptoms: one had the rash of dermatitis herpetiformis. All but one of the propositi of the relatives in whom were found small intestinal mucosal abnormalities themselves had the coeliac syndrome. It is concluded that a genetic factor is involved in the production of the enteropathy of dermatitis herpetiformis as in other forms of the coeliac syndrome.